Pleomorphic salivary adenoma

Glucuronidase activity by histochemical method was distributed in the acinar-rieopiastic epithelium in pleomorphic salivary adenoma (Murata and Miyaji, 1966),... 

Hirabayashi, S. 1999. Immunohistochemical detection of DNA topoisomerase type II a and Ki-67 in adenoid cystic carcinoma and pleomorphic adenoma of the salivary gland. 7. Oral Pathol. Med. 25 131—136. 

Pleomorphic adenoma (PA) is the most common salivary gland tumor. It occurs in all age groups, affects females more often than males, and may arise in either a major or a minor salivary gland location. When it originates in a major salivary gland, it is always encapsulated. Those of minor salivary gland origin are not encapsulated. 

Myoepitheliomas should be distinguished from pleomorphic adenomas and other salivary gland neoplasms. But the differential diagnosis may also include non-salivary gland lesions, depending on the predominant cell type in the myoepithelioma. For example, spindle cell myoepitheliomas should be differentiated from leiomyomas, schwannomas, and other spindle cell lesions. 

Prasad AR, Savera AT, Gown AM, et al. The myoepithelial im-munophenotype in 135 benign and malignant salivary gland tumors other than pleomorphic adenoma. Arch Pathol Lab Med. 1999 123(9) 801-806. 

Urethral and periurethral gland adenocarcinoma (female) Villous adenoma and adenocarcinoma of the bladder Extramammary Paget disease of the male external genitalia Pleomorphic adenoma of the salivary glands (male) Carcinoma of the salivary glands (male)... 

Salivary gland tumors (myoepithelial adenoma/ carcinoma, basal cell adenoma/carcinoma, pleomorphic adenoma)... 

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