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Plastic wake

Noradrenaline acts on three types of receptor. The ai receptors mediate the main excitatory effects of noradrenaline upon wake-active neurons in the dorsal raphe, basal forebrain, and elsewhere (Vandermaelen Aghajanian, 1983 Nicoll, 1988 Fort et al., 1995 Brown et al., 2002). The a2 receptors mediate inhibitory effects of noradrenaline, e.g. on noradrenaline neurons themselves and on cholinergic brainstem neurons (Williams et al., 1985 Williams Reiner, 1993). The (3-receptors modulate neurons in a more subtle fashion, increasing excitability via blockade of afterhyperpolarizations in hippocampal and cortical neurons (Haas Konnerth, 1983). Activation of (3-receptors also promotes synaptic plasticity via activation of the cyclic-AMP-dependent kinase (PKA) and cyclic AMP response element binding protein (CREB) signal transduction pathway (Stanton Sarvey, 1987 Cirelli et al., 1996). [Pg.34]

Department of Plastic and Reconstructive Surgery, Wake Forest University Health Sciences, Medical Center Blvd., Winston-Salem, NC 27157, USA E-mail nlevi wfubmc.edu... [Pg.223]

Second, it underlines the importance of viewing consciousness as a highly plastic, multivariate, dynamic function with an almost infinite set of possible instantiations. Third, it vindicates the comparative approach by showing that features of one canonical state (e.g., dreaming) can appear in another canonical state (e.g., waking) simply by changing one aspect of the control systems of the brain that normally maintain the discreteness of those states. [Pg.267]

Although this perspective parsimoniously encompasses the multiplicity of wake-sleep mechanisms, their plasticity and redundancy, the relative stability of total sleep, and rebounds following sleep deprivation, it suffers from a lack of critical, direct evidence. We have no better idea of what the major need-generated stimulus might be than we have of whether there is a master control mechanism. Only further, successful research can resolve these issues. [Pg.570]

For plastic beads with pp = 500 kg/m3 falling in air at ambient conditions, estimate the range of variation of the shedding frequency of the particle wake when the particle Reynolds number, based on the particle terminal velocity, varies from 500 to 1,000. For this particle Reynolds number range, what is the corresponding range of variation for the particle sizes ... [Pg.294]

Chemical manufacturing and petroleum refining have enriched our lives. Few individuals in the developed world stop to realize how the chemical industry has improved every minute of their day. The benefits of the industries are apparent from the time our plastic alarm clock tells us to wake up from a pleasant sleep on our polyester sheets and our polyurethane foam mattresses. As our feet touch the nylon carpet, we walk a few steps to turn on a phenolic light switch that allows electrical current to safely pass through polyvinyl chloride insulated wires. At the bathroom sink, we wash our face in chemically sanitized water using a chemically produced soap. [Pg.1]

Fillers of Plastics, (Ed. W. C. Wake), Iliffe Books, London 1971... [Pg.194]

The products discussed above touch us in every moment of our lives. We wake in the morning to an alarm clock in a polystyrene case we arise from our polyester blend sheets and slip on a pair of slippers glued with polyurethane glue. We flip the polymethylmethacrylate light switch and walk across a Nylon carpet to the bathroom. Our polymethylmethacrylate toothbrush is sitting on the Formica counter top. It has Nylon bristles. The soap we use to wash our face may be hydrocarbon derived sodium lauryl sulfate. We walk to the kitchen with polyvinyl chloride floors and sit at a Formica table. The polyethylene milk carton is at hand to supply the milk for the cereal stored in the polyethylene bag. It is eaten from a urea formamide bowl. The frying pan has a phenolformaldehyde plastic handle and a Teflon interior coating. [Pg.26]

After initial deformation, examination of the crystal surface, again by optical means, reveals a novel feature already discussed in fig. 8.3, namely, slip traces. These slip traces are the debris left in the wake of dislocations that have made their way to the crystal surface, leaving behind a jump across the relevant slip plane at its point of intersection with the crystal s surface. These slip traces bear a precise geometrical relation to the underlying crystalline geometry and thereby provide a central clue in ferreting out the microscopic origins of plastic deformation. [Pg.744]

The tool serves three primary functions, that is, heating of the workpiece, movement of material to produce the joint, and containment of the hot metal beneath the tool shoulder. Heating is created within the workpiece both by friction between the rotating tool pin and shoulder and by severe plastic deformation of the workpiece. The localized heating softens material around the pin and, combined with the tool rotation and translation, leads to movement of material from the front to the back of the pin, thus Ailing the hole in Ihe tool wake as the tool moves forward. The tool shoulder restricts metal flow to a level equivalent to the shoulder position, that is, approximately to the iniAal workpiece top surface. [Pg.1]

MPam / could be attributed entirely to crack wake effects, including frictional sliding, SiC particle bridging and plastic deformation of alloy bridges, rather than to changes in the crack-tip profile. Anderson [96] measured Kic in four-point bending for both a base composite and a SiC-reinforced composite and obtained 7.8 and... [Pg.312]

K.H. Allen, A.K. Hansrani and W.C. Wake, Adhesion and Adhesives Science, Technology and Applications, Intern. Conf., Gray College, Durham, Plastics and Rubber Inst., London. [Pg.162]

Crack closure can strongly affect fatigue and CF [45]. This phenomenon is based on crack surface contact during unloading, critically at stress intensity levels above zero and apphed-positive values. Crack wake contact is caused by corrosion debris, plasticity, crack path roughness, or phase transformation products each mechanism may be sensitive to aqueous environmental reactions [6]. To account for closure, dfl/dN is correlated with an effective stress intensity range that is defined operationally as the difference between appUed and the level where surface contact is resolved (see Data Analysis and Evaluation in this chapter). [Pg.305]


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