Plasmon resonance detection

Wang JL, Wang F, Chen HJ, Liu XH, Dong SJ (2008) Electrochemical surface plasmon resonance detection of enzymatic reaction in bilayer lipid. Talanta 75 666-670... 

The instrument based upon surface plasmon resonance detection (5,9-111 is now routinely used to measure the binding of an antigen (or antibody) to an immobilized antibody (or antigen) in a flow cell. The technology relies on the covalent immobilization of one of the interacting species and the detection of the adsorbed analyte. The sophistication of this expensive instrumentation makes its use difficult for routine investigations in many laboratories. Furthermore, the models used to extract the rate constants are not always appropriate to the kinetic data analysis [ 12-141. 

Du M, Zhou F (2008) Postcolumn renewal of sensor surfaces for high-performance liquid chromatography — surface plasmon resonance detection. Anal Chem 80 4225 230... 

Karlsson, R. Stahlberg, R., Surface plasmon resonance detection and multispot sensing for direct monitoring of interactions involving low-molecular-weight analytes and for determination of low affinities. Anal. Biochem. 1995, 228, 274-280... 

Based on the stereoselectivity of immunoglobulins, a new chiral sensor for the detection of low-molecular-weight analytes was developed. Using surface plasmon resonance detection, enantiomers of free, underivatized a-amino acids can be monitored in a competitive assay by their interaction with antibodies specific for the chiral center of this class of substances. The sensitivity to the minor enantiomer in non-racemic mixtiues exceeds cunently available methods therefore, such immuuoseusors can readily detect traces of enantiomeric impurities and are attractive for a range of applications in science and industry. 

Liedberg B. and Johansen K., Affinity biosensing based on surface plasmon resonance detection, in Biosensors Techniques and Protocols, ed. K. Rogers and A. Mulchandani (Totowa, NJ Humana Press 1998) Meth. BiotechnoL, 1, 31-54, 1998. 

With some detection technologies compounds can be screened in microarrays instead of plate wells. This requires that either the small molecule or the target be attached to a solid support, usually a glass slide, as shown in Figure 6.9. The other potential binding partner, which can be labeled (say with a fluorescent dye if fluorescence microscopy is used) or unlabeled (if surface plasmon resonance detection, discussed later, is to be used), is then exposed to the shde and interactions are detected. 

Whelan, R.J., Zare, R.N., Surface plasmon resonance detection for capillary electrophoresis separations. Ana/. Chem., 75,1542-1547, 2003. 

Surface Plasmon Resonance Sensors, Fig. 1 Variations on surface plasmon resonance detection (a) angular SPR, (b) spectral SPR, and (c) nanoparticle or local SPR. Details on each of the above techniques are provided in the text... 

S.D. Soelberg, R.C. Stevens, A.P. Limaye, C.E. Furlong, Surface plasmon resonance detection using antibody-linked magnetic nanoparticles for analyte capture, purification, concentration, and signal amplification. Analytical Chemistry 81 (2009) 2357-2363. 

Jonsson U. and Malmqvist M. (1992) Real time biospecific interaction analysis. The integration of surface plasmon resonance. Detection, general biospecific interface chemistry and microfluidics into one analytical system, Adv. Biosensors 2 291-336. 

Hartmann T, Ober D (2000) Biosynthesis and Metabolism of Pyrrolizidine Alkaloids in Plants and Specialized Insect Herbivores. 209. 207-243 Haseley SR, Kamerling JP, Vliegenthart JFG (2002) Unravelling Carbohydrate Interactions with Biosensors Using Surface Plasmon Resonance (SPR) Detection. 218 93-114... 

The branched polysaccharide dextran is assembled with alkanethiol-modified gold nanoparticles and the resulting nanocomposite is then functionalized to facilitate the specific binding of target biomolecules. This biorecognition process can be easily detected by particle plasmon resonance (PPR), based on the optical properties of gold nanoparticles [163]. 

Homola J., Dostalek J., Chen S., Rasooly A., Jiang S., Yee S.S., Spectral surface plasmon resonance biosensor for detection of staphylococcal enterotoxin B (SEB) in milk, Intern. J. Food Microbiology 2002 75 61-69. 

Spangler B.D., Wilkinson E.A., Murphyb J.T., Tyler B.J., Comparison of the Spreeta surface plasmon resonance sensor and a quartz crystal microbalance for detection of Escherichia coli heat-labile enterotoxins, Analytica Chimica Acta 2001 444 149-161. 

Koubova V., Brynda E., Karasova L., Skvor J., Homola J., Dostalek J., Tobiska P., Rosicky J., Detection of foodbome pathogens using surface plasmon resonance biosensors, Sensors and Actuators B 2001 74 100-105. 

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