Planorbis

The secondary alkanesulfonate tested has no significant toxic effect on Planorbis corneus. 

Snail, Planorbis corneus, shell vs. soft parts Common carp, Cyprinus carpio 760,588 Bq/kg FW vs. 27,468 Bq/kg FW 20... 

Figure 12.10. (a) Electrokinetic microinjector and (b) electropherogram generated from the removal and separation of cytoplasm samples from single nerve cells of Planorbis corneus, a pond snail.8 [Reprinted, by permission, from R. A. Wallingford and A. G. Ewing, Anal. Chem. 60 (No. 18), 1988, 1972-1975. Capillary Zone Electrophoresis with Electrochemical Detection in 12.7 pm Diameter Columns . 1988 by American Chemical Society.]... 

Anderson, B. B. and Ewing, A. G. Chemical profiles and monitoring dynamics at an individual nerve cell in Planorbis corneus with electrochemical detection. J. Pharm. Biomed. 19 15—32,... 

Chen, G. et al.. Observation and quantitation of exocytosis from the cell body of a fully developed neuron in Planorbis comeus, J. Neurosci., 15, llAl, 1995. 

Chien, J. B., Wallingford, R. A., andEwing, A. G, Estimation of free dopamine in the cytoplasm of the giant dopamine cell of Planorbis comeus by voltammetry and capillary electrophoresis, J. Neurochem., 54, 633-638, 1990. 

Early studies by Meulemans et al. used differential pulse voltammetry (see Chapter 11) to measure the concentration of electroactive drugs in the cytoplasm of cholinergic neurons of Aplysia californica and to determine rates of cellular uptake and clearance (108). Another report by Meulemans et al. described a needle tipped glass insulated platinum electrode for detection of intracellular serotonin in metacerebral neurons from Aplysia (109). Again differential pulse voltammetry was used to measure intracellular concentration of serotonin after cell stimulation, after injection of serotonin into the cell, and after extracellular treatment with tryptophan, a serotonin precursor. Serotonin concentration in resting untreated cells was determined to be 0.94 0.61 mM. Chen et al. have also used platinum electrodes with multiple pulse voltammetry to measure dopamine levels in the giant dopamine neuron of Planorbis comeus (110). 

Fox has compared the various values of pso, at 10° and 17°, and in the absence of COg, for the undiluted bloods of Chironomus larva, of Aremcola and Planorbis, and for the slightly diluted bloods of Tubifex, Daphnia and Ceriodaphnia. He obtained the results collected in Table XVII. 

Pounds, N., S. Maclean, M. L. Webley, D. Pascoe, and T. Hutchinson, 2008. Acute and chronic effects of ibuprofen in the mollusc Planorbis carinatus (Gastropoda Planorbidae). Ecotoxicol Environ. Safety 70 47-52. 

Figure 1. Schematic of the brain of Planorbis corneus showing electrode placement and microinjector.

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