Planorbis corneus

The secondary alkanesulfonate tested has no significant toxic effect on Planorbis corneus. 

Snail, Planorbis corneus, shell vs. soft parts Common carp, Cyprinus carpio 760,588 Bq/kg FW vs. 27,468 Bq/kg FW 20... 

Figure 12.10. (a) Electrokinetic microinjector and (b) electropherogram generated from the removal and separation of cytoplasm samples from single nerve cells of Planorbis corneus, a pond snail.8 [Reprinted, by permission, from R. A. Wallingford and A. G. Ewing, Anal. Chem. 60 (No. 18), 1988, 1972-1975. Capillary Zone Electrophoresis with Electrochemical Detection in 12.7 pm Diameter Columns . 1988 by American Chemical Society.]... 

Anderson, B. B. and Ewing, A. G. Chemical profiles and monitoring dynamics at an individual nerve cell in Planorbis corneus with electrochemical detection. J. Pharm. Biomed. 19 15—32,... 

Figure 1. Schematic of the brain of Planorbis corneus showing electrode placement and microinjector.

Figure 5. Oxidation current observed at 0.76 V vs SSCE at a carbon ring electrode implanted in the DA neuron of Planorbis corneus. Current observed following extracellular DA application (30 ih, 10 M at each arrow) Data obtained from staircase voltammograms (see text). 

The selectivity for monitoring DA in the presence of its metabolite DOPAC is increased following electrochemical oxidative pretreatment in pH 7.4 citrate-phosphate buffer. Structurally small carbon ring electrodes can be used to monitor the concentration of DA in the cytoplasm of single cells. Transport (uptake) of exogenous DA into the DA neuron of Planorbis corneus has been monitored intracellularly. Intracellular endogenous DA levels following extracellular application of ethanol have also been monitored. These experiments permit estimation of stored DA levels in the cell body of this neuron. 

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