Pituitary hormones Placental lactogen Prolactin

Chorionic Somatomammotropin. Three genes encode human chorionic somatomammotropin [11085-36-2] (hCS). These are located within a cluster of genes on human chromosome 17 which code for pituitary growth hormone [12629-01 -5] (GH-N), placental GH [109675-94-7J (GH-V), and three hCS molecules, ie, hCS-A, hCS-B, and hCS-V (1 3), also referred to as human placental lactogens. All of these molecules ate closely related to GH in stmcture (Fig. 1). Placental lactogens also exist in rodents and mminants however, these hormones are more closely related to prolactin than GH. 

Wallis, M. The molecular evolution of pituitary growth hormone, prolactin and placental lactogen a protein family showing variable rates of evolution. J. Mol. Evol. 16, 10-18 (1981) Zahner, H., Drautz, H., Weber, W. Novel approaches to metabolite screening. In Bioactive Microbial Products Search and Discovery (J. D. Bu Lock, L, J, Nisbet. D. J. Winstanley, eds,), pp. 51-70. Spec. Publ. Soc, Gen. Microbiol. 6, Academic Press, New York 1982... 

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