Physical Specification

The vast majority of modern resins are produced by the addition polymerization route and take the form of spherical beads. A few condensation polymer products remain available and these have an amorphous granular appearance. 

Gel resins usually shiny beads, clear to transmitted light. 

Macroporous resins usually dull beads of opaque or translucent appearance. 

Colour Without previous experience the identification of a resin by means of colour could be very misleading and is not advised. 

Effective size = mesh size (/xm) retaining 90% of the sieved sample 

---

Specifications. Specifications for many of the essential oils and artificial flavorings are available (66). Physical specifications encourage standardization and uniformity in basic flavor and perfume materials. Although compliance with specifications does not guarantee that flavor quaUty standards will be acceptable, the specifications fill a need and provide a valuable reference for the flavor industry. 

Production of carbon electrodes is a capital-intensive business. Two suppHers dominate the prebaked market. Carbon paste producers are more numerous and tend to serve local markets. There is no international standard for the threaded joints on carbon electrodes. Manufacturers of straight pin carbon electrodes have followed the physical specifications adopted for graphite electrodes (37). Unified standards do not exist for pinless joints resulting in limited interchangeability among brands. Electrode diameters are offered in both English and metric sizes with no restrictions on new or unique diameters. 

The CBMS II is to be deployed aboard wheeled reconnaissance vehicles. The platforms include a light armored vehicle, the US Army XM1135 Stryker Nuclear, Biological, Chemical Reconnaissance Vehicle (NBCRV),23 and two vehicles for the US Marine Corps Joint Services Lightweight Nuclear, Biological, Chemical Reconnaissance System (JSLNBCRS) 24 the HMMWV and a wheeled, light armored vehicle very much like the XM1135 Stryker. Consequently the volume, mass, and power available to the instrument are limited. Table 4.1 lists the current physical specification and objective requirement for each parameter. 

As Talibudeen (1 ) states, it is unwise to assign them simply to the interlayer, edge, and planar surfaces of clays in the way that Bol t et al. (22) and Schouwenberg and Schuffelen (20) did, an interpretation that has become widely accepted. Several reasons can be adduced for the strong adsorption of K which involve physical (specific) and charge (coulombic effects). The occurrence of several types of sites in one sample could also reflect interstratification within relatively large crystallites (31) or, as has recently been suggested by Nadeau et al. 

One point that arises from study of these E2-E3 structures, is that there is a degree of specificity in their physical interactions. The biochemical data extends the idea of physical specificity in E2-E3 interactions to functional specificity. An example of this is the Brcal-Bardl heterodimer, which interacts physically with UbcH7 and UbcHSC, but is only active with UbcHSC. There appear to be two consequences of E2 specificity variability in the strength of a particular E3 response and variability in the type of ubiquitin modification. 

The GMP regulations require reprocessing procedures to be written, and it is customary but not required that NDAs/ANDAs contain procedures covering foreseeable deviations from physical specifications (e.g., color, capped tablets, deviations from hardness specifications, etc.). If the NDA/ANDA contains a reprocess provision, the applicant must produce scientific data to establish that the procedure will result in a product that is equivalent to the original product. 

The firm failed to document how each specific supplier is evaluated in order to assure their products meet specified requirements as required by their Vendor/Supplier Qualification SOP. Additionally, the firm failed to complete adequate purchasing controls in that they fail to ensure that the initial audit of suppliers is conducted prior to the supplier s acceptance, firm fails to assure components meet specifications (physical specifications), and fails to document in-process rejects. 

Table 2.8. Whole black pepper chemical and physical specifications.

Table 3.14. Whole cardamom chemical and physical specification.

The chemical and physical specification for whole coriander is given in Table 10.3 and for ground coriander in Table 10.4. 

ASTA recommends a moisture limit of 10% in the whole spice. Ash and acid-insoluble ash should be no greater than 6 and 1%, respectively. Tables 18.6 and 18.7 show the chemical and physical specifications for the whole and ground spice, including the FDA DALs for the whole spice. 

Table 18.6. Whole anise chemical and physical Table 18.7. Ground anise chemical and physical specifications. specifications.

ASTA suggest maximum moisture levels of 10%. Ash and acid-insoluble ash should be less than 10 and 2%, respectively. Tables 22.3 and 22.4 summarize the typical chemical and physical specifications, including the FDA s DAL, for whole celery and ground celery, respectively. 

In order to formulate the optimal tablet, various properties should be considered, including drug-excipient compatibility, flowability, lubricity, appearance, dissolution, and disintegration [2], The prepared tablet must also meet physical specification and... 

The use of conical twin screw extruders for the extrusion of wood filled PVC has also been presented (156). The characterisation of apparent viscosity for PVC wood fibre extrusion has been carried out and quadratic models used to establish tolerances within which the dimensional and physical specifications were achieved (69). 

Design of experiments methodology was used to determine the maximum variability in viscosity which a poly(vinyl chloride)/wood fibre profile extrusion process was able to tolerate. Fourteen critical dimensions, profile bow, shrinkage, Young s modulus, and stress and strain under maximum load were measured. Quadratic models were created from the dimensional measurements, bow, maximum tensile stress, pressure in the die adaptor and the current drawn by the screw drive, and used to establish the tolerances within which the dimensional and physical specifications were simultaneously achieved. 

Finally, it is emphasized that Table 8.1 gives typical physical specifications for a number of bakery shortenings adjustments can and should be made to meet requirements for a particular product or equipment line. The values given are meant as guidelines, and a complete ingredient specification should be developed in consultation with shortening suppliers. 

---