Phosphate, Dibasic Anhydrous

BP Anhydrous calcium hydrogen phosphate JP Anhydrous dibasic calcium phosphate PhEur Calcii hydrogenophosphas anhydricus USP Dibasic calcium phosphate [Pg.93]

A-TAB calcium monohydrogen phosphate calcium orthophosphate Di-Cafos AN dicalcium orthophosphate E341 Emcompress Anhydrous Fujicalin phosphoric acid calcium salt (1 1) secondary calcium phosphate. [Pg.93]

Anhydrous dibasic calcium phosphate is used both as an excipient and as a source of calcium in nutritional supplements. It is used particularly in the nutritional/health food sectors. It is also used in pharmaceutical products because of its compaction properties, and the good flow properties of the coarse-grade material.The predominant deformation mechanism of anhydrous dibasic calcium phosphate coarse-grade is brittle fracture and this reduces the strain-rate sensitivity of the material, thus allowing easier transition from the laboratory to production scale. However, unlike the dihydrate, anhydrous dibasic calcium phosphate when compacted at higher pressures can exhibit lamination and capping. This phenomenon can be observed when the material represents a substantial proportion of the formulation and is exacerbated by the use of deep concave tooling. This phenomenon also appears to be independent of rate of compaction. [Pg.93]

Anhydrous dibasic calcium phosphate is abrasive and a lubricant is required for tableting, for example 1% w/w magnesium stearate or 1 % w/w sodium stearyl fumarate. [Pg.93]

Two particle-size grades of anhydrous dibasic calcium phosphate are used in the pharmaceutical industry. Milled material is typically used in wet-granulated or roller-compacted formulations. The unmilled or coarse-grade material is typically used in direct-compression formulations. [Pg.93]

Avastin Avastin is used for the treatment of colorectal cancer. It is supplied in 100 and 400 mg dosages. The 100 mg formulation consists of 240 mg a,a-trehalose dihydrate, 23.2 mg sodium phosphate (monobasic, monohydrate), 4.8mg sodium phosphate (dibasic, anhydrous), 1.6mg polysorbate 20 and water-for-injection. [Pg.166]

PEG-Intron PEG-Intron is used for the treatment of hepatitis C. The product consists of a covalent conjugate of the recombinant interferon- -2b with monomethoxy polyethylene glycol (PEG) supplied in vials with 74/rg, 118.4/rg, 177.6/rg, or 222/rg of the active ingredient and 1.11 mg sodium phosphate (dibasic,anhydrous),l.ll mg sodium phosphate (monobasic, dihydrate), 59.2 mg sucrose, and 0.074mg polysorbate 80. The powder is reconstituted with sterile water-for-injection. [Pg.166]

Formulation Aranesp is formulated as a sterile, colorless, preservative-free protein solution for intravenous (IV) or subcutaneous (SC) administration. There are two formulations the polysorbate solution includes excipients such as polysorbate 80, sodium phosphate monobasic monohydrate, sodium phosphate dibasic anhydrous, and sodium chloride in water-for-injection while the albumin solution contains albumin, sodium phosphate monobasic monohydrate, sodium phosphate dibasic anhydrous, and sodium chloride in water-for-injection. The pH for both formulations is 6.2 + 0.2. [Pg.171]

A new formulation of a saline laxative, Visicol, that is useful to prepare patients for procedures, was approved for use in 2001. Each 2-g tablet contains 1.102 g sodium phosphate monobasic monohydrate and 0.398 g sodium phosphate dibasic anhydrous, for a total of 1.5 g sodium phosphate. Visicol tablets, taken in two doses of 30 g approximately 12 hours apart, induce diarrhea that rapidly and effectively cleanses the entire colon. Each administration has a purgative effect for approximately 1 to 3 hours. [Pg.475]

Per 1 mL 2.5 mg albumin (human) 1.2 mg sodium phosphate monobasic monohydrate 1.8 mg sodium phosphate dibasic anhydrate 0.7 mg sodium citrate 5.8 mg sodium chloride 6.8 pg citric acid in WFI, USP... [Pg.448]

Per 1 mL polysorbate solution 0.05mg/mL polysorbate 80 2.12mg/mL sodium phosphate monobasic monohydrate 0.66mg/mL sodium phosphate dibasic anhydrous 8.18mg/mL sodium chloride (pH 6.2 0.2)... [Pg.456]

Per 1 mL 1.36 mg glycine 36.0 mg mannitol 1.04mg sodium phosphate dibasic anhydrous 0.36 mg sodium phosphate monobasic monohydrate... [Pg.463]

Calcium phosphate, dibasic anhydrous Dicafos-A Budenheim... [Pg.3679]

Table I Pharmacopeial specifications for calcium phosphate, dibasic anhydrous.

Galcium phosphate, dibasic anhydrous calcium phosphate, tribasic. [Pg.98]

E202 Potassium Sorbate 609 E341 Calcium Phosphate, Dibasic Anhydrous 93... [Pg.882]

Calcium Phosphate, Dibasic Anhydrous 94 270-325-2 Benzalkonium Chloride 63... [Pg.885]

Calcium phosphate, dibasic anhydrous 0.1-0.187 Moisture surface adsorbed does not form hydrate... [Pg.77]

Two formulations contain excipients as follows polysorbate solution contains 0.05 mg of polysorbate 80, 2.12 mg of sodium phosphate monobasic monohydrate, 0.66 mg of sodium phosphate dibasic anhydrous, and 8.18 mg of sodium chloride in water for injection, LISP (per 1 mL) at pH 6.2 + 0.2. Albumin solution contains 2.5 mg of albumin (human), 2.23 mg of sodium phosphate monobasic monohydrate, 0.53 mg of sodium phosphate dibasic anhydrous, and 8.18 mg of sodium chloride in water for injection, LISP (per 1 mL) at pH 6.0 + 0.3. [Pg.339]

Each vial also contains 1.36 mg of glycine, 36.0 mg of mannitol, 1.04 mg of sodium phosphate dibasic anhydrous, and 0.36 mg of sodium phosphate monobasic monohydrate. [Pg.345]

Adipoyldiamino) bis [2,4,6-triiodobenzoic acid] 3,3 -(Adipoyldiimino) bis (2,4,6-triiodobenzoic acid). See lodipamide Adipoyl hydrazide. See Adipic acid dihydrazide Adi-pure . See Adipic acid Adipyinitrile. See Adiponitrile Adjunct B. See Sodium phosphate dibasic anhydrous... [Pg.123]

Albrite Disodium Phosphate Anhyd. (Tech.). See Sodium phosphate dibasic anhydrous Aibrit Disodium Phosphate Dihydrate (Tech.). [Pg.135]

Aquastar 175. See Phosphoric acid Aquastar 211. See Sodium phosphate Aquastar 221. See Sodium phosphate dibasic anhydrous... [Pg.333]

Dibasic sodium phosphate. See Sodium phosphate dibasic anhydrous Dibasic sodium phosphate dihydrate. See Sodium phosphate dibasic dihydrate Dibasic sodium phosphate dodecahydrate. See Sodium phosphate dibasic dodecahydrate Dibasic sodium phosphate heptahydrate. See Sodium phosphate dibasic heptahydrate Dibasic zinc stearate. See Zinc stearate... [Pg.1219]

Disodium acid phosphate. See Sodium phosphate dibasic anhydrous Disodium 5-amino-4-hydroxy-3-(phenylazo) naphthalene-2,7-disulfonate. See Acid red 33 Cl 17200... [Pg.1521]