Pharmacogenomics: benefits

Discovery of new diagnostic and prognostic indicators and biomarkers of therapeutic response, and prediction of patients most likely to benefit from the diug and use in general pharmacogenomic studies (Fig. 2)... 

Fig. 4.1 Expected benefits of pharmacogenomics in drug research and development.

In order to design alternative therapeutic strategies and to identify variances that specify the SCA patient population who will benefit from a safe and effective therapy, the present strategies of pharmacogenomics will involve either a targeted can-... 

But assume that those barriers are overcome and a pharmaceutical company markets an important drug based on pharmacogenomics. Assume, for example, that pharmacogenomics research allows the firm to know which 80% of the population will benefit from the drug, which 10% will receive absolutely no benefit, and which 10% will be seriously harmed by it. The short-term consequence would be to improve health outcomes of everyone, not just the 80% who would benefit but the other 20% who should not take the drug. The dynamic consequences are less clear. If such pharmacogenomic... 

It is apparent that pharmacogenomics creates a new way of assessing the risks and benefits of drugs of all kinds at a point in time when systemic... 

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