Pharmacogenomics: general

Discovery of new diagnostic and prognostic indicators and biomarkers of therapeutic response, and prediction of patients most likely to benefit from the diug and use in general pharmacogenomic studies (Fig. 2)... 

In addition to these generalized approaches of genomics and proteomics, it has been predicted that pharmacogenomics may revolutionize drug discovery and treatment for the individual, based on the following (and with some of the consequences noted) [12] ... 

Although there are data on the variability of the treatment response for each of these classes of agents, there are no systematic studies on the reasons for variance in the treatment response to steroids or theophylline. Therefore, this chapter will focus on the specific pharmacogenomics of /1-agonists and inhibitors of the cysteinyl-leukotriene pathway [18, 30] and on general considerations related to pharmacogenomic mechanisms. 

The language used in research studies suggests that scientists still grapple with labels to describe ethnic groups in a way that does not misinform or cause undue generalization of results. What is a Caucasian What does it mean to be Asian Research in pharmacogenomics will drive a re-examination of these labels in search of more meaningful descriptive terms. 

Pharmacogenomics and Minority Populations General Population Survey Questionnaire, 337... 

Kalow, W., and A.G. Motulsky, "General Conclusions and Future directions," In Kalow W., Meyer U.A., Tyndale R.F., Pharmacogenomics, New York Marcel Dekker, pp. 389-395 (2001). 

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