Pentosan polysulphate

Xylan sulphates, known also as pentosan polysulphates (PPS), are permanently studied with regard to their biological activities [3,419-422]. Usually, sulphuric acid, sulphur trioxide, or chlorsulphonic acid are employed as sul-phating agents alone or in combination with alcohols, amines or chlorinated hydrocarbons as reaction media [423]. [Pg.52]

Maffrand JP, Herbert JM, Bernat A, Defreyn G, Delebassee D, Savi P, Pinot JJ, Sampol J. Experimental and clinical pharmacology of pentosan polysulphate. Semin Thrombosis Haemostasis 1991 17 (Suppl. 2) 186-198. [Pg.157]

JF Innes, AR Barr, M Sharif. Efficacy of oral calcium pentosan polysulphate for the treatment of osteoarthritis of the canine stifle joint secondary to cranial cruciate ligament deficiency. Veterinary Rec 146 433-437, 2000. [Pg.309]

SW McLeskey, L Zhang, BJ Track. Effects of AGM-1470 and pentosan polysulphate on tumorigenicity and metastasis of FGF-transfected MCF-7 cells. Br J Cancer 73 1053-1062, 1996. [Pg.309]

Todd NV, Morrow J, Doh-Ura K, DeaUer S, O Hare S, FarUng P, Duddy M, Rainov NG (2005) Cerebroventricular infusion of pentosan polysulphate in human variant Creutzfeldt-Jakob disease. J Infect 50 394-396... [Pg.380]

The degradation of proteoglycan by an elastase-enriched neutral protease preparation from leukocytes has been shown to be inhibited by pentosan polysulphate, an anti-inflammatory agent, presumably by formation of a complex between the drug and the proteoglycan. ... [Pg.649]

Another possibility is the application of mesenchymal precursor cells (MFCs) loaded in hydrogel with soluble factor as pentosan polysulphate [34], Frith et al showed evidence that this system has significant potential as both a delivery vehicle for MFCs and as a matrix for fibrocartilage tissue engineering applications. [Pg.432]

Frith, J.E., Cameron, A.R., Menzies, D.J., Ghosh, P., Whitehead, D.L., Gronthos, S., Zannettino, A.C., Cooper-White, J.J. An injectable hydrogel incorporating mesenchymal precursor cells and pentosan polysulphate for intervertebral disc regeneration. Biomaterials 34(37), 9430-9440 (2013)... [Pg.441]

Andrews, J.L., Ghosh, R, Lentini, A., TemaL B. (1983) The interaction of pentosan polysulphate with human neutrophyl elastase and connective tissue matrix components. Chemico-Biological Interactions, 47, 157-173. [Pg.69]

Pentosan polysulphate (Mw 3000 g/mol) Whey proteins/anion exchange DC Comparison to dextran sulfate (Mw SO OOO g/mol) [611... [Pg.68]

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