Injectable hydrogel

Figure 8. In situ gel formation and degradation behavior of composite hydrogels. From A to E showed the photograph took at Id, 3d, 7d, lOd and 14d after injection respectively (From left to right S4, S3, S2 and SI). F and G presented the photograph took at 2h and 6h after Pluronic FI27 hydrogel injection.

Figure 9. Photograph of tissue samples from injection site after composite hydrogel injection for 14d ( X 400). A Control group B S3 hydrogel injection group C S1 hydrogel injection group.

The hydrophilic/hydrophobic SIN composition of PDMS with poly(HEMA) and poly(AAC) were proposed as a potential apphcation for high-permeability soft contact lenses. Other sUicone-containing IPNs for contact lenses include polymerization of MMA in the presence of polymerized methacryloxypropyl trimethoxysilane, the cross-linking of a polymeric hydrogel of a copolymer of NVP during the final compression or injection-moulding process. 

Such hydrogels have been suggested to be suitable for biotechnological applications (DNA delivery vehicles, cell encapsulation) [28]. Recently, amphiphilic dibock copolypeptide hydrogels of KigoL2o were used in an in vivo study where the hydrogels were injected into the mouse forebrain. Evaluation of samples displayed substantial tissue integration with little or no detectable toxicity in the central nervous system [148]. 

Burdick JA, Anseth KS (2002) Photoencapsulation of osteoblasts in injectable RGD-modified PEG hydrogels for bone tissue engineering. Biomaterials 23 4315-4323... 

Minh KN, Lee DS (2010) Injectable biodegradable hydrogels. Macromol Biosci 10 563-579... 

Haines-Butterick L, Rajagopal K, Branco M et al (2007) Controlling hydrogelation kinetics by peptide design for three-dimensional encapsulation and injectable delivery of cells. Proc Natl Acad Sci 104 7791-7796... 

Yan CQ, Altunbas A, Yucel T et al (2010) Injectable sobd hydrogel mechanism of shearthinning and immediate recovery of injectable beta-hairpin peptide hydrogels. Soft Matter 6 5143-5156... 

Branco M, Wagner N, Pochan D et al (2009) Release of model macromolecules from selfassembling peptide hydrogels for injectable delivery. Biopolymers 92 318-318... 

We prepared a phenol-containing hyaluronan derivative, which was inter-molecularly coupled by HRP to yield a crosslinked hydrogel (Scheme 27). The sequenhal injection of this hyaluronan derivative and peroxidase formed... 

Biomineralization of Hydrogels Based on Bioinspired Assemblies for Injectable Biomaterials... 

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