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PDGFR receptor

PDGF Isoforms consist of homo- and heterodimers of A- and B-polypeptide chains and homodimers of C- and D-polypeptide chains PDGFR Consists of PDGFR a and (3 receptors Embryonic development, particularly in the formation of the kidney, blood vessels, and various mesenchymal tissues. Proliferation of connective tissues, glial and smooth muscle cells... [Pg.566]

PDGFR Platelet-derived growth factor receptor... [Pg.285]

Board, R. and Jayson, G. 2005. Platelet-derived growth factor receptor (PDGFR) a target for anti cancer therapeutics. Drug Resistance Updates 8(1-2), 75-83. [Pg.289]

PDGFR platelet-derived growth factor receptor RAGS repulsive axon guidance signal... [Pg.966]

Imatinib (STI571) is an inhibitor of the tyrosine kinase domain of the Bcr-Abl oncoprotein and prevents the phosphorylation of the kinase substrate by ATP. It is indicated for the treatment of chronic myelogenous leukemia (CML), a pluripotent hematopoietic stem cell disorder characterized by the t(9 22) Philadelphia chromosomal translocation. This translocation results in the Bcr-Abl fusion protein, the causative agent in CML, and is present in up to 95% of patients with this disease. This agent inhibits other activated receptor tyrosine kinases for platelet-derived growth factor receptor (PDGFR), stem cell factor (SCF), and c-kit. [Pg.1307]

See other pages where PDGFR receptor is mentioned: [Pg.104]    [Pg.104]    [Pg.156]    [Pg.568]    [Pg.569]    [Pg.985]    [Pg.1192]    [Pg.1271]    [Pg.240]    [Pg.4]    [Pg.514]    [Pg.179]    [Pg.419]    [Pg.419]    [Pg.423]    [Pg.432]    [Pg.453]    [Pg.6]    [Pg.12]    [Pg.506]    [Pg.544]    [Pg.67]    [Pg.165]    [Pg.719]    [Pg.719]    [Pg.130]    [Pg.108]    [Pg.117]    [Pg.86]    [Pg.347]    [Pg.358]    [Pg.362]    [Pg.363]    [Pg.387]    [Pg.409]    [Pg.132]    [Pg.339]    [Pg.460]    [Pg.247]    [Pg.132]    [Pg.31]   


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PDGFR

PDGFR (platelet-derived growth receptors

PDGFR factor receptor

Platelet-derived growth factor receptor PDGFR)

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