Pasteurella pestis

Initial Discoveries. Xylose isomerase activity was initially found in 1953 in extracts of Lactobacillus pentosus (14), followed by similar activities in extracts of Pseudomonas hydrophila and Pasteurella pestis in the mid-1950s (15-17). An enzyme activity that was found to convert glucose to fructose was discovered in 1957 (18). This activity, found in sonicated extracts from Pseudomonas hydrophila, was enhanced in the presence of... 

Streptococci, staphylococci, pneumococci, gonococci, meningococci, Haemophilus influenzae, H. ducreyi, Calymmatobacterium granulomatis. Vibrio comma. Vibrio cholerae, E. coli, Pasteurella pestis. Shigella. 

They are generally toxic to most body tissues, and are less potent than exotoxins. They are typified by the following, Escherichia coli (wound infection and septicaemia), Klebsiella pneumoniae (urogenital tract infections). Shigella dysenterlae (dysentery). Salmonella typhosa (typhoid fever), Pasteurella pestis (bubonic plague) and Pseudomonas aeruginosa (wound infections and septicaemia). Not all of these endotoxins are fully characterized, and some toxic mechanisms are obscure. 

Winter, C.C., Cherry, W.B., Moody, M.D. 1960. An unusual strain of Pasteurella pestis isolated from a fatal human case of plague. Bull. World Health Organ. 23 408-409. 

Burrows TW. Virulence of Pasteurella pestis and immunity to plague. Ergebn Mikrobiol. 1963 37 59-113. 

Eremin et al. (1965) have precipitated carbohydrate material with ethanol after alkaline hydrolysis of cultures of Whitmore s bacillus Pseudomonas pseudomailer), Pasteurella pestis, and Vibrio comma, and have subjected these polyoses to infrared spectroscopy. All spectra had strong absorption at 1660 and 1550 cm the former was related to double-bond vibrations and the latter was associated with stretching vibrations of C—N. The latter absorption was almost completely absent in the spectrum of a complex from V. comma. Absorption at 970 cm (the C=C double bond in the trans position) and traces of absorption at 790 cm characteristic of the 1 — 3 bond were always present. A polysaccharide from the cell wall of P. pestis had a wide band at 1170-1000 cm the low intensity bands at 1190 and 1160cm indicated the presence of P—O—Me and P—O—Et groups. The spectrum of a complex from Whitmore s bacillus differed from the others by the presence of a band at 1735 cm due to esters of fatty acids. 

Mycobacterium bovis Mycobacterium leprae Mycobacterium tuberculosis Neisseria gonorrhoeae Neisseria meningitidis Pasteurella pestis Pseudomonas pseudomallei Salmonella typhi Streptococcus pneumoniae Treponema pallidum Treponema pertenue Vibrio cholerae... 

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