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Parkinsonian rats

COMMENT I would dispute it within the dopamine system itself And I would dispute it about Parkinson s disease. I think that if you did a proper neuropsychological exam that you would pick up even smaller depletion effects. I think if you are looking for an overt complete terminal Parkinson situation, yes, you need a 99 percent depletion. But part of the problem is that the Parkinson situation involves not only the nigrostriatal system but also the mesolimbic dopamine system. There are plenty of studies in rats, and it is very easy to produce a Parkinsonian rat with a very discrete... [Pg.352]

Studer, L., Tabar, V. and McKay, R. D. Transplantation of expanded mesencephalic precursors leads to recovery in parkinsonian rats. Nat. Neurosci. 1 290-295,1998. [Pg.516]

Kirik, D. et al. (2002). Reversal of motor impairments in parkinsonian rats by continuous intrastriatal delivery of L-dopa using rAAV-mediated gene transfer. Proc. Natl. Acad. Sci. USA 99(7), 4708-4713. [Pg.218]

Perese DA, Ulman J, Viola J, Ewing SE, Bankiewicz KS (1989) A 6-hydroxydopamine-induced selective parkinsonian rat model. Brain Res 494 285-293. [Pg.193]

Connor B (2001) Adenoviral vector-mediated delivery of glial cell line-derived neurotrophic factor provides neuroprotection in the aged parkinsonian rat. Ctin Exp Pharmacol Physiol 28 896-900. [Pg.103]

T Fnjikawa, N Kanda, A Shimada, M Ogata, 1 Snznki, 1 Hayashi, K Nakashima. Effects of sesamin in Acanthopanax sencticosus Harms on behavioral dysfunction in rotenone-induced Parkinsonian rats. Biol Pharm Bull 28 169-172, 2005. [Pg.629]

Marin C, Papa S, Engber TM et al (1996) MK-801 prevents levodopa-induced motor response alterations in parkinsonian rats. Brain Res 736 202-205... [Pg.131]

Marin C, Jimenez A, Bonastre M et al (2001) LY293558, an AMPA glutamate receptor antagonist, prevents and reverses levodopa-induced motor alterations in Parkinsonian rats. Synapse 42 40—47... [Pg.135]

Breysse N, Amalric M, Salin P (2003) Metabotropic glutamate 5 receptor blockade alleviates akinesia by normalizing activity of selective basal-ganglia structures in parkinsonian rats. J Neurosci 23 8302-8309... [Pg.138]

Studer L, Tabar V, McKay RDG. Transplantation of mesencephalic precursors leads to recovery of Parkinsonian rats. Nat Neurosci 1998, 1, 290-295. [Pg.361]

Hargus, G., Cooper, O., Deleidi, M., et al. Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and rednce motor asymmetry in Parkinsonian rats. Proc. Natl. Acad. Sci. USA 107, 15921-15926... [Pg.323]

See other pages where Parkinsonian rats is mentioned: [Pg.353]    [Pg.67]    [Pg.95]    [Pg.162]    [Pg.711]    [Pg.162]    [Pg.711]    [Pg.67]    [Pg.323]    [Pg.203]   
See also in sourсe #XX -- [ Pg.18 ]



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