Function packaging

To understand how such computer packages function, consider the simple flowsheet in Figure 13.13a. This involves an isomerization of Component A to Component B. The mixture of A and B from the reactor is separated into relatively pure A, which is recycled, and relatively pure B, which is the product. No byproducts are formed and the reactor performance can be characterized by its conversion. The performance of the separator is to be characterized by the recovery of A to the recycle stream (rA) and recovery of B to the product (rB). 

Kada M, Smith L. Advancements in stacked chip scale packaging (S-CSP), provides system-in-a-package functionality for wireless and handheld applications. Proceedings of Pan Pacific Microelectronics Symposium Conference 2000. p 1-7. 

Design and Configure LIMS Package Functional Design Specification production... 

The most common applications of paper, paper-board, and cardboard are in blister lidding stock and in over-the-counter (OTC) outer packaging. Because paper, paperboard, and cardboard offer virtually no moisture or gas barrier, they are typically part of the secondary pharmaceutical container. To provide additional protection, paper can be laminated or coated with a variety of materials. More commonly, when paper is involved in critical packaging functions, it is the only one component of a multicomponent system that offers optimal environmental protection to the drug environment. ... 

A logical approach to packaging optimisation is, first of all, to define the packaging function, followed by selection of the materials, then testing the performance of the packaging to ensure that it will meet all the product design and functional requirements that were identified in the Product Design Report. 

Where relevant, process detail should include environmental conditions (humidity, temperature, time, duration, etc.) documentation of procedures, tests, etc. details of records to be kept (GMP) written instructions for operators reference to machinery to be employed etc. It can therefore be concluded that an effective level of specification is required for any pharmaceutical product and the appropriate detail must be similarly treated for the packaging function. As specification detail and tests associated with specifications frequently show a tendency to expand with time, it is important that these are constantly reviewed in terms of both the quality level necessary and the procedures by which materials are judged as satisfactory. Although the setting-up of a specification system is relatively simple, maintenance and updating frequently cause problems. It is therefore recommended that any specification distribution system have the absolute minimum of recipients. 

GMP is not simply the Orange Guide and the interpretation of it, but ongoing improvements in pharmaceutical quality. This means more control over the total packaging function and a greater use of computerised data, records and information. 

Tip 9 Stick to the specification when evaluating package functions. 

While packaging functions can be grouped in various ways, one common grouping is contaimnent, protection, utility, and communication. While grouping the functions in this way makes discussion easier, it should be emphasized that the boundaries between the groups are not always clear-cut, and in many cases a single package feature serves multiple functions. 

Containment is the most basic package function. It is not possible to transport a liqnid or grannlar prodnct withont containing it in some fashion. For larger prodncts that conld conceivably be transported without a container, contaimnent simplifies the task by making it possible to handle a number of products as a unit—the reason most people bring their groceries home in a bag. 

Polyurethane has a range of packaging functions and is often used as filling material in tablet containers. Polyurethanes do not have a good resistance to acids and alkali. 

Fig. 7. Typical coextruded sheet structures used for barrier food packaging. Functional properties (a) retortability, high oxygen and moisture barrier (three extruders) (b) heat sealability, oxygen and moisture barrier, low taste and odor transfer, thermoformabdity (four extruders) (c) oxygen and moisture barrier, uv light protection, heat sealability, ther-moformability (five extruders).

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