P fatty acid

De Caterina, R., Liao, J.K., and Libby, P., Fatty acid modulation of endothelial activation, Am. J. Clin. Nutr., 71, 213S, 2000. 

Degradation procedures analogeus to those used for mycobactin P (see above) showed the aromatic residue to be salicylic acid (2-hydroxy-6-methylbenzoic acid in mycobactin P) and the hydroxy acid to be (+)-( -hydroxybutyric acid ((-)-3-hydroxy-2-methylpentanoic acid in mycobactin P). Fatty acid side chains substantially different from those in mycobactin P a minor component contains a s-octadec-2-enoic acid (identical to the principal product in mycobactin P). The major substituents in the fatty acid side chain are Cis to C21 fragments of unknown constitution. 

Rinaldo P. Fatty acid transport and mitochondrial oxidation disorders. Seminars in Liver Disease 2001 21 489-500. 

Kuhajda, F. P. Fatty acid synthase and cancer new application of an old pathway. Cancer Res 66 (2006) 5977-5980. 

Alii, P. M., Pinn, M. L., Jaffee, E. M., McFadden, J. M. and Kuhajda, F. P., Fatty acid synthase inhibitors are chemopreventive for mammary cancer in neu-N transgenic mice. 

Kapur, P., Rakheja, D., Roy, L. C. and Hoang, M. P., Fatty acid synthase expression in cutaneous melanocytic neoplasms, Mod Pathol 18 (2005) 1107-1112. 

Simopoulos, A.P, Fatty acid composition of skeletal muscle membrane phospholipids, insulin resistance and obesity, Nutr. Today, 2, 12, 1994. 

Zhang Y, Li F, Patterson AD, Wang Y, Krausz KW, Neale G, Thomas S, Nachagari D, Vogel P, Vore M, Gonzalez FJ, Schuetz JD (2012) Abcbll deficiency induces cholestasis coupled to unpaired P-fatty acid oxidation in mice. J Biol Chem 287, 24784-94. 

Fig. 150. Thin-layer chromatogram of phospholipids and other polar lipids of bovine milk [159 a]. 1 carbohydrate (lactose) and protein, 2 sphingomyelin, 3 phosphatidyl choline, 4 phosphatidyl serine, 5 phosphatidyl inositol, 6 phosphatidyl ethanolamine, 7 cerebroside dihexoside ( ), 8 cerebroside mono-hexoside ( ), P fatty acids, 10 neutral lipids. Adsorbent Silica gel HR. Solvents I, chloroform-methanol-water-28% aqu. ammonia (130 + 70+8 + 0.5) II, chloroform-acetone-methanol-acetic acid-water (50 + 20 + 10 + 10 + 5). Time 40 min in each direction. Indicator charring with chromic sulphuric acid solution...

Simopoulos, A.P., Fatty acids, in Designer Foods, Pharmafoods, Nutraceuticals, Goldberg, I. (Ed.), International Thomson Pubhshing, New York, 1994, pp. 355-392. 

Rowe, R.I., Eckhert, C.D. Boron is required for zebrafish embryogenesis. J. Exp. Biol. 1999 202 1649-1654. Samman, S., Chow, J.W.Y., Foster, M.J., Ahmad, Z.I., Phuyal, J.L., Petocz, P. Fatty acid composition of edible oils derived from certified organic and conventional agricultural methods. Eood Chem. 2008 109 670-674. 

CH3-[CH2],8-C00H. M.p. 75 C. A fatty acid occurring as glycerides in peanut and other vegetable oils. 

CH3 [CHJb-COOH. M.p. 31 5"C, b.p. 268-270 C. A fatty acid, occurring in wool as the potassium salt, as esters in fusel oil, and as glycerides in cows and goats milk and coconut and palm oils. 

The lower members of the series are liquids soluble in water and volatile in steam. As the number of carbon atoms in the molecule increases, the m.p. and b.p. rise and the acids become less soluble in water and less volatile. The higher fatty acids are solids, insoluble in water and soluble in organic solvents. 

C12H24O, CH3 [CH,]io COOH. Needles, m.p. 44 C, b.p. 225"C/I00mm. A fatty acid occurring as glycerides in milk, spermaceti, laurel oil, coconut oil, palm oil and other vegetable oils. The metal salts are widely used. 

C27H55COOH. Glistening scales m.p. 89 C. A straight-chain, saturated fatty acid, that occurs in many natural waxes. 

Colourless liquid. B.p. 286 C/100 mm., insoluble in water. Oleic acid occurs naturally in larger quantities than any other fatty acid, being present as glycerides in most fats and oils. It forms one third of the total fatty acids of cow s milk. A crude grade from inedible tallow is used in the production of lubricants, detergents, resins and other products. 

CH3-[CHi]5.CH CH-[CH2]g-C02H. A white solid, m.p. 43-44°C, which is present in small quantities in animal fats and in milk. It is the only naturally occurring fatty acid with the trans configuration. 

If the original ester is a fat or oil and produces an odour of acrolein when heated, it may be a glyceride. Esters of ethylene glycol and of glycol with simple fatty acids are viscous and of high b.p. They are hydrolysed (method I) and the ethyl alcohol distilled ofl. The residue is diluted (a soap may be formed) and acidified with hydrochloric acid (Congo red paper). The acid is filtered or... 

The basic flow sheet for the flotation-concentration of nonsulfide minerals is essentially the same as that for treating sulfides but the family of reagents used is different. The reagents utilized for nonsulfide mineral concentrations by flotation are usually fatty acids or their salts (RCOOH, RCOOM), sulfonates (RSO M), sulfates (RSO M), where M is usually Na or K, and R represents a linear, branched, or cycHc hydrocarbon chain and amines [R2N(R)3]A where R and R are hydrocarbon chains and A is an anion such as Cl or Br . Collectors for most nonsulfides can be selected on the basis of their isoelectric points. Thus at pH > pH p cationic surfactants are suitable collectors whereas at lower pH values anion-type collectors are selected as illustrated in Figure 10 (28). Figure 13 shows an iron ore flotation flow sheet as a representative of high volume oxide flotation practice. 

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