Oxobutyl esters

The best catalyst to perform this reaction is the stable binuclear [Ru(02CH)(C0)2-(PPh3)]2 complex, which makes possible the transformation of bulky alcohols such as steroid derivatives with retention of configuration at the propargylic carbon atom [57], and the preparation of y3-oxopropyl esters from propargylic alcohols as well as y-oxobutyl esters from butynol (Scheme 8.16) [56]. 

Adenosine 5"-(trihydrogen diphosphate) (5 ->5") ester with 3-(amino-carbonyl)-l-p-D-ribofuranosylpyridinium hydroxide inner salt, C-143 Adenosine 5 -(trihydrogen diphosphate) (5 ->5 ) ester with 1,4-dihydro-l-p-D-ribofuranosyl-3-pyridinecarboxamide, C-143 Adenosine 5 -(trihydrogen diphosphate) (5 5) ester with D-ribose, A-37 Adenosine 5 -(trihydrogen diphosphate) 3 -(dihydrogen phosphate) 5 -[3-hydroxy-4-[[3-[(2-mercaptoethyl)amino]-3-oxopropyl]amino]-2,2-dimethyl-4-oxobutyl] ester, C-144... 

CN (S)-carbonic acid 4-[2-[[2-(acetylamino)-4-(methylthio)-1 -oxobutyl]amino]ethyl]-1,2-phenylene diethyl ester... 

CJH13CI2NO3 58012-30-9) see Pirisudanol 4-(4-chloro-l-oxobutyl)-a,a-dimethylbenzeneaceticacid ethyl ester... 

Cuscutic resinoside A (1 tetradecanoic acid, (115)-[[6-deoxy-3-(9-(6-deoxy-a-L-mannopyranosyl)-4-0-[(2/ ,3R)-3-hydroxy-2-niethyl-l-oxobutyl]-a-L-nianno-pyranosyl]oxy]-intramol. l,2 -ester) was obtained from the ethyl acetate-soluble fraction of a methanol extract prepared from the seeds of Cuscuta chinensis Lam. The purification of this compound employed a combination of column and preparative-scale HPLC. The structure was deduced from spectroscopic evidence and acid hydrolysis 14). The degradative process gave convolvuUnolic acid, nilic acid, and L-rhamnose. The sugar components were identified by GC analysis after being converted to their thiazolidine derivatives. This disaccharide has a unique macrocyclic lactone, which is placed between C-1 and C-2 of the first rhamnose moiety. 

Oxobutyl)cyclopentanone-2-carboxylic Acid Ethyl Ester. 

There have been synthesized in this laboratory over the past several years a variety of phosphonic acids which are nominally isosteric with natural monophosphate esters. Of this collection of compounds three are of particular interest for the present work. These are (S)-3,4-dihydroxybutyl-1-phosphonic acid (A)(1), an isosteric analogue of sn-glycerol-3-phosphate 4-hydroxy-3-oxobutyl-l-phosphonic acid (B)( ), an isosteric analogue of dihydroxyacetone phosphate and 5-carboxy-4-hydroxy-4-methylpentyl-l-phosphonic acid (C)(3), an isosteric analogue of 5-phosphomevalonate. 

OXOBUTYL)CYCLOPENTANONE-2-CARBOXYLIC ACID ETHYL ESTER. 

Oxobutyl)cyclopentanone-2-carboxylic acid ethyl ester Cyclopentanecarboxylic acid, 2-oxo-1-(3-oxobutyl)-, ethyl ester (10) (61771-81-1)... 

OXOBUTYL)C YCL0PENTAN0NE-2-CARB0XYLIC ACID ETHYL ESTER... 

OXOBUTYL)CYCLOPENTANONE-2-CARBOXYLIC acid ethyl ester. 

R ]]-N- 2,4-Dikyd roxy-3,3-dimethyt-I -oxobutyl - -alanine 2-[(dlchloroacetyl)amino]-3-hydroxy-3-(4-nitrophen-ylipropyt ester pantothenic acid ester with 2,2-dichloro-N-[3 hydrOxy-a-(hydroxymethyii-p-nilrophenethylJacetamide ... 

Diethyl (3-oxobutyl)phosphonate 354 The methiodide obtained from 4-(diethylamino)-2-butanone (7.15 g, 0.05 mole) and methyl iodide (7.15 g) is heated with triethyl phosphite (0.25 mole, 41.5 g) for 1 h at 130°. After cooling, the triethylmethylammonium iodide formed (10.6 g, 87%) is filtered off and washed with benzene. On evaporation the filtrate and wash-benzene leave a pale yellow oil which is distilled in a vacuum (yield 8.4 g, 81 % b.p. 89-97°/ 0.08 mm) and on redistillation gives the phosphonic ester (7.5 g, 72%), b.p. 96-98°/0.14 mm, nD25 1.4352. 

Since the ester obtained in this way still contains one active hydrogen atom, it can be condensed with a second molecule of methyl vinyl ketone, which yields ethyl 2-acetyl-5-oxo-2-(3-oxobutyl)hexanoate ... 

The formation of diethyl (3-oxobutyl)phosphonate from triethyl phosphite and 3-oxobutyl acetate can be formulated also as taking place through a phosphorane intermediate. As further examples, the phosphoranes 587 have been prepared from the benzylidene derivatives 583, 584 585 and 586 Careful hydrolysis of the phosphoranes 587 with one equivalent of water in diethyl ether leads to the corresponding 588, which in turn tautomerize to the ketonic alkylphosphonic dimethyl esters 589, which can also be obtained independently by the addition of dimethyl hydrogenphosphonate to the original benzylidene compounds the latter, when heated, generate the dihydro-1,2-oxaphosph(V)oles 590. In the same way, the esters 593 have been obtained from the eth-ylidene compounds 591 via the respective oxyphosphoranes 592 (R = Me, Et, or EtO) ". ... 

The acylation of phosphonic carbanions with carboxylic esters is a procedure which has received widespread attention and employed to prepare the protected dimethyl (3,4-dihydroxy-2-oxobutyl)phosphonate 608 and dimethyl [(35)-3-methyl-2-oxo-5-octynyljphosphonate (609), intermediates required in natural product synthesis d An example of intramolecular acylation is the formation of 610 by the action of potassium tert-butoxide on ethyl 2-[(ethoxy)methylphosphinoyl]benzoate d. Acylations of lithiated phosphonoyl carbanions provide dialkyl [(l-formyl)alkyl]phosphonates d ... 

The amine-immobilized silica-alumina catalyst achieved a good yield of 2-cyano-5-oxo-2-(3-oxobutyl) hexanoic acid ethyl ester from the Michael reaction between nitrile and a,P-unsaturated ketone (Table 7.6). Notably, the reaction using a mixture of triethylamine and unfunctionahzed sihca-alumina gave a lower yield than the amine-immobilized silica-alumina, and both triethylamine and silica-alumina were inactive alone for the reaction. In general, the conjugate addition of nitrile compounds to a,P-unsaturated ketones requires strong base or transition metal... 

Diacetatopalladium. See Palladium diacetate Diacetic ether. See Ethylacetoacetate Diacetin (INCI). See Glyceryl diacetate Diacetone. See Diacetone alcohol Diacetone acrylamide CAS 2873-97-4 EINECS/ELINCS 220-713-2 Synonyms Acrylamide, N-(1-1dimethyl-3-oxobutyl)- 4-Acrylamido-4-methyl-2-pentanone DAA Diallyl ester acetic acid N-(1,1-Dimethyl-3-oxobutyl) acrylamide N-(1,1-Dimethyl-3-oxobutyl)-2-propenamide N-(2-(2-Methyl-4-oxopentyl)) acrylamide N-(2-Methyl-4-oxo-2-pentyl) acrylamide 2-Propenamide, N-(1,1-dimethyl-3-oxobutyl)-Classification Acrylamide Empirical C9H15NO2... 

Hydroxy-3-(3-oxo-l-pheitylbutyl)-2/f-l-benzopyian-2-one, see Warfarin 4-Hydroxy-3-(l-pheityl-3-oxobutyl)couniarin, see Warfarin 6-Hydroxy-2/f-pyridazin-3-one, see Maleie hydrazide 6-Hydroxy-3(2/f)-pyridazinone, see Maleie hydrazide l-Hydroxy-2,2,2-trichloroethylphosphonie acid dimethyl ester, see Trichlorfon Hylemox, see Ethion... 

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