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Oxiconazole

Sample preparation Dissolve lotion containing 50 mg oxiconazole in 50 mL MeOH, dilnte a 5 mL aliqnot to 50 mL with mobile phase, inject an ahquot. Shake cream containing 50 mg oxiconazole with 50 mL chloroformiMeOH 50 50 for 30 min (Caution Chloroform is a carcinogen ), make np to 100 mL with MeOH, centrifuge at 4000 rpm at 4° for 15 min, filter, dilnte fivefold with MeOH. [Pg.481]

Mobile phase MeOH 20 mM ammonium acetate buffer 85 15 [Pg.481]

Milano, J. Morsch, L.M. Gonalves Cardoso, S. LC method for the analysis of Oxiconazole in pharmaceutical formulations, J.Pharm.BiomedAncd., 2002, 30, 175 180. [Pg.481]

Sample preparation Inject an ahquot of a 100 xg/mL solution in MeOH. [Pg.481]

Column 125 x 4 5 im LiChrospher 100 RP8 Mobile phase MeCN 20 mM ammonium acetate buffer 75 25 Flowrate 1 Detector UV 254 [Pg.481]


Because of their limited, activity, small spectmm, and side effects, the older topical antimycotics have generally been surpassed by newer antimycotic chemotherapeutic agents. These newer antimycotics for topical use iaclude the imida2ole derivatives clotrimazole, miconazole, econazole, isoconazole, sulconazole, fenticonazole, oxiconazole, bifonazole, butoconazole, ziaoconazole, tioconazole, and the triazole derivative, terconazole (Table 2) (5—7). The iatroduction of the azole derivatives represents a milestone ia the treatment of mycoses. [Pg.253]

Dichlorophenyl)-2-(1 H-imidazol-1 -yl)ethanone oxime Oxiconazole nitrate cis-2-(2,4-Dichlorophenyl)-2-(1 H-... [Pg.1627]

C3H4N2 288-32-4) see Bifonazole Butoconazole Clotrimazole Eprosartan Fenticonazole Isoconazole Ketoconazole Miconazole Neticonazole hydrochloride Omoconazole nitrate Oxiconazole Ozagrel 1/f-imidazole lithium salt (C,H3LiN2 55986-39-5) see Flutrimazole 2-imidazolidinone... [Pg.2401]

Nystatin (Mycostatm) Oxiconazole (Oxistat) Posaconazole (Noxafil) S taconazole (Ertaczo) T binafine (LamisU) Triamcinolone ... [Pg.36]

Mupirocin (Bactroban) Naftifme (Naftin) Neomycin Sulfate, Topical (Myciguent) Nystatin (Mycostatin) Oxiconazole (Oxistat) Penciclovir (Denavir) Permethrin (Nix, Elimite) Pimecrolimus (Elidel)... [Pg.44]

Topical azole derivatives include the imidazoles bifonazole, clotrimazole, econazole, ketoconazole, miconazole, oxiconazole, lanoconazole, flutrima-zole and sertaconazole. These drugs show activity against the dermatophytes Epidermophyton, Mi-crosporum and Trichophyton. They are also effective against the yeasts Candida albicans and Pityrospo-rum orbiculare. Local side effects include pruritus, erythema and local irritation. Allergic dermatitis is rare. [Pg.480]

Contraindications Not for ophthalmic use hypersensitivity to oxiconazole or any other azole fungals... [Pg.920]

Imidazoles clotrimazole econazole nitrate ketoconazole miconazole nitrate oxiconazole nitrate tioconazole... [Pg.613]

Miconazole, oxiconazole, ketoconazole, sulconazole, clotrimazole (along with betamethasone dipropionate), terbinafine (SEBIFIN), naftifine, butenafine, tolnaftate, nystatin, amphotericin B, cyclopirox... [Pg.450]

An imine moiety can, interestingly, be interposed in the ether linkage used to connect the two halogenated aromatic rings. The requisite oxime (55-1) is obtained in a straightforward fashion by reaction of imidazo acetophenone (54-2) with hydroxyl-amine alkylation with a,2,3-trichlorotoluene leads to oxiconazole (55-2) [60]. [Pg.274]

Topical 100,000 units/g cream, ointment, powder 100,000 units vaginal tablets Oxiconazole (Oxistat)... [Pg.1065]

The topical imidazoles, which currently include clotrimazole, econazole, ketoconazole, miconazole, oxiconazole, sulconazole, and sertaconazole, have a wide range of activity against dermatophytes (epidermophyton, microsporum, and trichophyton) and yeasts, including Candida albicans and Pityrosporum orbiculare (see Chapter 48). [Pg.1289]

Oxiconazole nitrate Oxistat Stearyl alcohol, polysorbate 60 NF, cetyl alcohol Benzoic acid... [Pg.216]


See other pages where Oxiconazole is mentioned: [Pg.253]    [Pg.1627]    [Pg.1720]    [Pg.1725]    [Pg.605]    [Pg.605]    [Pg.606]    [Pg.606]    [Pg.1519]    [Pg.1519]    [Pg.2346]    [Pg.2346]    [Pg.2348]    [Pg.2396]    [Pg.2448]    [Pg.594]    [Pg.607]    [Pg.595]    [Pg.609]    [Pg.44]    [Pg.106]    [Pg.282]    [Pg.345]    [Pg.362]    [Pg.244]    [Pg.492]    [Pg.601]    [Pg.920]    [Pg.459]    [Pg.675]    [Pg.1289]    [Pg.1289]   
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