Ovarian tumors thecoma

Tumors derived from the sex cords or ovarian mesenchyme compose 5% to 12% of all ovarian neo-plasms. 413 Benign tumors in the fibroma-thecoma group are relatively common. Other sex cord-stromal tumors and mesenchymal tumors are rare. The most common malignant sex cord- stromal tumor is granulosa cell tumor, which composes 1% of 2% of all malignant ovarian tumors. There are two types of granulosa cell tumors an adult type that occurs mainly in postmenopausal... 

Wilms tumor protein-1 (WT-1) Nephroblastoma, mesothelioma, metanephric adenoma, ovarian serous carcinoma AML, desmoplastic small round cell tumor, endometrial stromal sarcoma, uterine leiomyosarcoma, granulosa cell tumor, thecoma, rhabdoid tumor Kidney, mesothelial cells, granulosa cells, Sertoli cells, fallopian tube endometrial stroma, spleen... 

In a study of human ovarian tumors, McKay et al. (1949) found the quantity of histochemically reactive lipids to be directly related to the functional activity of these tumors. Moreover, in tumors with estrogenic activity the reactive lipids were confined to thecal cells, in either granulosa cell tumors or thecomas. In tumors with progestational activity, the lipids were in the lutein cells. Deane and Fawcett (1952), working with experimental tumors produced by transplanting ovaries to the spleens of... 

Psammoma bodies, which are tiny calcifications,are found in CT in approximately 10% of serous epithelial ovarian cancers (Fig. 10.4). Calcifications are also foimd in benign ovarian stromal tumors, e.g.,Breimer tumors or thecomas. These tumors are typically sohd and tend to show extensive coarse calcifications. 

---