Osmitrol - Mannitol

Mannitol (Osmitrol) is used for the promotion of diuresis in the prevention and treatment of the oliguric phase of acute renal failure as well as for the reduction of IOP and the treatment of cerebral edema Urea (Ureaphil) is useful in reducing cerebral edema and in die reduction of IOE Glycerin (Osmoglyn) and isosorbide (Ismotic) are used in the treatment of acute glaucoma and to reduce IOP before and after eye surgery. 

Mannitol (OsmitroL others) [Osmotic Diuretic] Uses Cerebral edema, T lOP/ICP, renal impair, poisonings Action Osmotic diuretic Dose Test dose 0.2 g/kg/dose IV over 3-5 min if no diuresis w/in 2 h, D/C Oliguria 50-100 g IV over 90 min T lOP 0.5-2 g/kg IV over 30 min Cerebral edema 0.25-1.5 g/kg/dose IV >30 min Caution [C, ] w/ CHF or volume overload Contra Anuria, dehydration, HE, PE Disp Inj SE May exacerbate CHF, N/V/D Interactions t Effects OF cardiac glycosides X effects OF barbiturates, imipramine, Li, salicylates EMS Monitor ECG for hypo-/hyperkalemia (T wave changes) OD May cause dehydration, t urine frequency/amount hypotension and CV collapse symptomatic and supportive... 

Mannitol (Osmitrol) is a six-carbon sugar that does not undergo appreciable metabolic degradation. It is not absorbed from the gastrointestinal tract and there-... 

AccessMedicine Print Chapter 15. Diuretic Agents Oral 1.25, 2.5 mg tablets Mannitol (generic, Osmitrol)... 

Peds. Cardiac arrest w/ torsades 25-50 mg/kg/dose IV Caution [B, +] Contra Heart block Disp Inj 10, 20, 40, 80, 125, 500 mg/mL bulk powder SE CNS depression, D, flushing, heart block Interactions T CNS depression W/ antidepressants, antipsychotics, anxiolytics, barbiturates, hypnodcs, narcotics EtOH T neuromuscular blockade W/ aminoglycosides, atracurium, gallamine, pancuronium, tubocurarine, vecuronium EMS Monitor ECG for changes Mannitol (Osmitrol) [Osmotic Diuretic] Uses Tx cerebral edema (T ICP) Action Diuretic Dose Adults. 0.5-2 g/kg slow IV Peds. 0.2-0.5 g/kg IV over 60 min Caution [C, ] Contra Pulm edema, CHF, cerebral bleeding Disp Inj, sol 5% (50 mg/mL) 10% (100 mg/mL) 15% (150 mg/mL) 20% (200 mg/mL) 25% (250 mg/mL) SE N/V, HA, dizziness, edema, blurred vision, diuresis, dehydration Interactions Interferes w/ blood transfusions EMS Use caution to prevent extravasation (use large vein) rebound T in ICP has been noted about 12 h post administration... 

As their name suggests, osmotic diuretics such as mannitol (Osmitrol), isosorbide (Ismotic), and glycerin (Osmoglyn) draw fluid from the tissues of the body through principles of osmosis. Osmotic diuretics are typically given to treat or prevent acute renal failure (kidney failure). They may also be used to relieve intracranial pressure (swelling of the brain) in cases of head injury or hydrocephalus. 

Glycerin Isosorbide (Ismotic) Mannitol (Osmitrol) Urea (Ureaphil) Atropine sulfate Cyclopentolate HC1 Dipivefrin HC1 Epinephrine HC1 Epinephrine borate Homatropine hydrobromide (Isopto Homatropine) Scopolamine hydrobromide Tropicamide (Mydriacyl Ophthalmic) ... 

The osmotic dinretics and related agents consist of mannitol (Osmitrol), nrea (Ureaphil), glycerin (glycerol, Osmoglyn), and isosorbide (Hydronol). Mannitol and urea are nonelectrolytes, which are freely filterable, and undergo very little or no metabolism or renal tubular resorption. 

Isosorbide (Ismotic) Mannitol (Osmitrol) Urea (Ureaphil)... 

The client with a head injury is experiencing increased intracranial pressure. The neurosurgeon prescribes the osmotic diuretic mannitol (Osmitrol). Which intervention should the nurse implement when administering this medication ... 

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