Organic secondary ion mass

Delcorte, A., Medard, N., Bertrand, R. (2002) Organic secondary ion mass spectrometry sensitivity enhancement by gold deposition. A flZ. Chem., 74,4955 968. 

Nygren, H., Malmberg, P. (2007) High-resolution imaging by organic secondary ion mass spectrometry. Trends BiotechnoL, 11,499-504. 

Delcorte, A., Bertrand, P. (2005) Metal salts for molecular ion yield enhancement in organic secondary ion mass spectrometry a critical assessment. Anal. Chem., 77, 2107-2115. 

P. (2002) Organic secondary ion mass spectrometry sensitivity enhancement... 

Benninghoven, A. Organic Secondary Ion Mass Spectrometry (SIMS) and Its Relation to Fast Atom Bombardment (FAB). Int. J. Mass Spectrom. Ion Phys. 1983,46,459-462. 

Spectrometric Analysis. Remarkable developments ia mass spectrometry (ms) and nuclear magnetic resonance methods (nmr), eg, secondary ion mass spectrometry (sims), plasma desorption (pd), thermospray (tsp), two or three dimensional nmr, high resolution nmr of soHds, give useful stmcture analysis information (131). Because nmr analysis of or N-labeled amino acids enables determiaation of amino acids without isolation from organic samples, and without destroyiag the sample, amino acid metaboHsm can be dynamically analy2ed (132). Proteia metaboHsm and biosynthesis of many important metaboUtes have been studied by this method. Preparative methods for labeled compounds have been reviewed (133). 

It is worth noting, prior to citing actual metal atom studies, the recent secondary ion mass spectrometry (SIMS) on an argon matrix-isolated propene sample, demonstrating the applicability of SIMS analysis to the characterization of matrix-isolated species. The same group h s reported the first C NMR spectra of organic molecules trapped in an argon matrix. ... 

Several years later, the next step in the application of MS-MS for mixture analysis was developed by Hunt et al. [3-5] who described a master scheme for the direct analysis of organic compounds in environmental samples using soft chemical ionisation (Cl) to perform product, parent and neutral loss MS-MS experiments for identification [6,7]. The breakthrough in LC-MS was the development of soft ionisation techniques, e.g. desorption ionisation (continuous flow-fast atom bombardment (CF-FAB), secondary ion mass spectrometry (SIMS) or laser desorption (LD)), and nebulisation ionisation techniques such as thermospray ionisation (TSI), and atmospheric pressure ionisation (API) techniques such as atmospheric pressure chemical ionisation (APCI), and electrospray ionisation (ESI). 

Barber, M. Vickerman, J.C. Wolsten-holme, J. Secondary Ion Mass Spectra of Some Simple Organic Molecules. J. Chem. Soc., Faraday Trans. 1 1980, 76, 549-559. 

Franzen, G. et al.. The anionic structure of room-temperature organic chloroaluminate melts from secondary ion mass-spectrometry. Org. Mass Spec., 21,443,1986. 

Todd, P. J., Schaaff, T. G., Chaurand, P., and Caprioli, R. M. (2001). Organic ion imaging of biological tissue with secondary ion mass spectrometry and matrix-assisted laser desorption/ionization. J. Mass Spectrom. 36 355-369. 

Secondary Ion Mass Spectrometer Design Considerations for Organic and Inorganic Analysis... 

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