Opium tincture

Opium tincture 5 mgAnL (morphine) 0.6 mL four times daily... 

Soaking plants parts in alcohol (ethanol) creates a tincture. In this process, pharmacologically active constituents of the plant are extracted by the alcohol. Tinctures do not contain the complete spectrum of substances that exist in the plant or crude drug, only those that are soluble in alcohol. In the case of opium tincture, these ingredients are alkaloids (i.e., basic substances of plant origin) including morphine, codeine, narcotine = noscapine, papaverine, narceine, and others. 

Opioids. Activation of opioid receptors in the enteric nerve plexus results in inhibition of propulsive motor activity and enhancement of segmentation activity. This antidiarrheal effect was formerly induced by application of opium tincture (paregoric) containing morphine. Because of the CNS effects (sedation, respiratory depression, physical dependence), derivatives with peripheral actions have been developed. Whereas diphenoxylate can still produce clear CNS effects, loperamide does not Lullmann, Color Atlas of Pharmacology... 

Paregoric Opium Tincture (lauda- Pitocin Oxytocin... 

Liquid anhydrous morphine equiv. to 10 mg per mL (c-//) Opium Tincture, Deodorized Ranbaxy)... 

Caution - Opium tincture contains 25 times more morphine than paregoric. Do not confuse opium tincture with paregoric this may lead to an overdose of morphine. 

Opium Diarrhea caused by poisoning until the toxic material is eliminated from the Gl tract use in children (opium tincture only) convulsive states such as those occurring in status epilepticus, tetanus, and strychnine poisoning (Paregor/c only). Oxycodone ... 

The more widely used paregoric (camphorated opium tincture) is equally effective and is frequently used in combination with other antidiarrheal agents. Codeine also has been used for short-term symptomatic treatment. 

II High Yes Codeine, morphine, meperidine Same as Schedule 1 (Demerol), opium poppy, opium tincture (Laudanum), granulated opium, powdered opium, raw opium, oxycodone (OxyContin, Percocet), thebaine... 

Opioid derivatives used to treat diarrhea are listed in Table 27-3. Opium tincture (laudanum) and camphorated opium tincture (paregoric) are naturally occurring opiates that are very potent inhibitors of peristalsis. These natural agents are still available for treating diarrhea, but they have essentially been replaced by newer opioids such as diphenoxylate and loperamide. These newer opioids are somewhat less potent but may produce fewer side effects. 

The alkaloids derived from opium are collectively known as opiates. Morphine, codeine, and thebaine are well-known opium derivatives. Paregoric is an opium tincture (opium in an alcohol mixture). 

P. somnifemm (opium poppy) (Papaveraceae) [latex opium (laudanum = opium tincture) users - Hector Berlioz (inspired Symphonie Fantastique), Elizabeth Barrett Browning, Samuel Taylor Coleridge, (inspired poem Kubla Khan), reputed agent in attempted suicide of Napoleon Bonaparte (12 April 1814) suicide of Robert Clive, Helen of Troy, Sherlock Holmes, Modest Mussorgsky, Florence Nightingale, Edgar Allen Poe,... 

Opium. An extract of opium, containing a mixture of the total alkaloids of opium, is available as an alcoholic aqueous solution. It is available us Deudorixed Opium Tincture (IS mg/mL of morphine base) and Paregoric (2 mg/mL of morphine base). These are used primarily for the treatment of diarrhea. 

Synonyms Opium Opium tincture Hydrochloride of opium alkaloids. Camphorated tincture of opium... 

OPIUM TINCTURE, Opii tinctura The tincture is an effective and cheap antipropulsive... 

Crude opium is used as the starting material for the extraction of morphine (of which 80% is methylated to codeine), codeine and noscapine. Opium, according to the pharmacopoeia, is used for the preparation of opium tincture, which is an excellent remedy for the treatment of tropical diarrhoea. 

The antitussive effect of codeine and noscapine is dealt with in R05, the spasmolytic effect of papaverine is dealt with in A03A and the constipating effect of opium tincture is mentioned in A07. 

Through the centuries opium was used as an analgetic, sedative, hypnotic, and euphoric in the form of powders, alcoholic extracts (opium tincture, laudanum), syrups, and elixirs. It was even smoked, after the use of tobacco became prevalent. 

Chloroform Elixir. Take li ounces each chloroform, tincture of opium, tincture of camphor, and aromatic spirit of ammonia 20 flrops oil of cinnamon, and 2 ounces brandy. This is an excellent mixture for colic. Dose, i fluid drachm. 

Powdered opium, U.S.R, is a light brown, bitter, fine powder, supplied for clinical use in capsule, tablet, or pill form. The average adult dose is 0.06 gram taken orally. This is equivalent to 6 mgm of morphine, the official morphine content of opium being 10% by weight. Opium tincture (Laudanum, deodorized opium tincture), U.S.R, is a hydroalcoholic solution containing 10% of opium (1.0% of morphine). The average adult dose is 0.6 to 1.5 mL (equivalent to 6 to 15 mgm of morphine), taken orally. 

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