Ointment properties

Features Active therapeutic ingreds. may be dissolved in either the oil or water phase or physically dispersed as a suspension in the emulsion Reguiatory Meets BP specs, tor wool alcohols ointment Properties Pale yel. soft solid, pract. odorless mostly sol. in min. oil, IPM partly sol. in acetone, anhyd. ethanol and IPA insol. in water m.p. 39-45 C HLB 4.0 acid no. 0.25 max. flash pt. > 100 C 6% cone. 

Uses Self-emulsifying ingred., ointment base, emollient, spreading agent for cosmetics and medical ointments Properties Cream-colored soft wax HLB 1 Emalex LWS-5 [Nihon Emulsion]... 

Uses Surfactant, emulsif er for cleansing prods., hair conditioners, wave sets, face, body and hand creams and lotions, pharmaceutical ointments Properties Amber cl. liq. acid no. 2 max. sapon. no. 70-80 hyd. no. 70-80 Fancol HCO40 [Fanning]... 

Chem. Descrip. Dimethicone copolyol meadowibamate Uses Emollient, slip agent for skin care prods. gloss aid, conditioner for hair care prods. pigment dispersant, gloss aid, substantivity agent for colored cosmetics softener and conditioner for topical pharmaceutical ointments Properties SI. yel. wax insol. in water acid no. 5 max. 

Uses Emollient, lubricant, solubilizer, emulsifier, plasticizer for cosmetics, pharmaceuticals, sun preps. emollient and surfactant in aq. and hydtoalcoholic systems conditioner for shampoos superfatting agent for hand soaps and waleriess cleaners imparts soft, nonsticl f%l in creams and ointments Properties Yel. flakes, char, odor water sol. m.p. 45 C min. acid no. 2 max. ... 

Uses Emulsifier for cosmetics (creams, skin care lotions, makeup bases, pigmented prods., hair creams, after-bath prods.) and pharmaceuticals (ointments, suppositories), esp, lipophilic anhyd. ointments Properties Liq., faint odor sol. in min. and veg. oils, sol. hot in ethanol insol. in water vise. 200 mPa S HLB 1.8 acid no. 15 max. sapon. no. 170-190 hyd. no. 55-70 pH 7 100% cone. 

Uses Surfactant for makeup, deansers, body creams and lotions, shampoos, moisturizing creams, topical pharmaceutical ointments Properties Lt. golden gran. sol. in IPM, ethyl acetate, water insol. in castor oil, propylene glycol, ethanol, min. oil, glycerol HLB 7.0 acid no. 35 max. 

Uses Emulsifier for cosmetic and pharmaceutical w/o creams and ointments Properties Lt. yish. fluid dens. 0.880-0.900 g/cm vise. 35-55 mm /s acid no. 5 max. sapon. no. 160-200 hyd. no. 40-60 Storage 6 mos. min. shelf life when stored in original containers under suitable conditions... 

Uses Emulsifier, gellant, stabilizer, wetting agent, detergent, dispersant, solubilizer for cosmetics (skin care, makeup bases, shaving, bath oils, hair care, depilatories, deodorants, antiperspirants) and pharmaceuticals (creams, ointments) Properties Wax sol. 10% in 95 C ethanol, propylene glycol insol. in water, vaseline oil HLB 15.3 m.p. 44 C acid no. 1 max. hyd. no. 45-60 cloud pt. 90 C pH 6.5-7.5 (10% aq.) 100% cone. 

Uses Emulsifier for silicone, min. oil deresination agent, detergent and emulsifier in pulping operations emulsifier and wetting agent for pharmaceutical ointments Properties APHA <80 liq. sp.gr. 0.975 HLB 11.4 cloud pt. 40 C (1% aq.) pH 5-7 Sinopol 1107L [Sino-Japan]... 

Uses Emulsifier for paraffin dyeing aux. emulsifier, dispersant, wetting agent for food emulsifier and wetting agent tor pharmaceutical ointments Properties APHA < 80 (40 C) solid sp.gr. 0.950 (40 C) HLB 10.8 pH 5-7 100% cone. 

Uses Emulsifier disinfectant softener antistat gum dispersant preventive agent in petroleum and oil pipe cleaning active ingted. for contraceptive ointments Properties Gardner < 2 Iiq, sp.gr. 0.980 pH 7.0 50% act. in water Sinotex L7 [Sino-Japan]... 

Chem. Descrip. Lanolin/lanolin alcohol blend in petrolatum base Uses Primary w/o emulsifier, aux. o/w emulsifier emollienL nnoisturizer for skin and hair care prods., pharmaceutical ointments Properties Gardner < 6 solid sol. in min. oil, IPM disp. in triolein dens. 7.4 Ib/gal m.p. 4046 C flash pt. 425 F. 

Uses Emulsifier for health food industry, special nutritional applies., dietetic prods., phannaceutical drugs, aerosols, cryst. suspensions, emulsions, fat infusions, liposomes, ointments Properties Waxy... 

Uses Emulsifier for w/o systems, stabilizer for o/w systems, wetting agent, dispersant, conditioner, emollient, tackifierfor pharmaceutical ointments Properties Yel. to It. tan solid m.p. 3946 C acid no. 10 max. iodine no. 12-20 sapon. no. 95-110 hyd. no. 60-85 100% cone. 

Sahcyhc acid USP, EP, and other pharmacopeia grades are used medically as antiseptic, disinfectant, antifungal, and keratolytic agents. Sahcyhc acid is formulated in lotion or ointment formulations for the treatment of dandmff, eczema, psoriasis, and various parasitic skin diseases. Because the keratolytic property of this aromatic acid has use in the safe removal of dead skin cells from the surface of healthy skin, the acid is used in concentrated sahcyhc acid solutions or suspensions to remove warts and corns. In more dilute form, sahcyhc acid preparations have found use in dandmff and eczema treatment. Sahcyhc acid has been considered and found effective by the Advisory Committees to the FDA in various over-the-counter (OTC) dmg regulated uses. Among these are acne products, dermatitis, dry skin, dandmff and psoriasis products, and foot care products (24). 

The NF and reagent grades are employed in the pharmaceutical industry which makes use of benzyl alcohol s local anesthetic, antiseptic, and solvent properties (17—20). It also finds use in cough symps and drops ophthalmic solutions bum, dental (21), and insect repeUant solutions and ointments and dermatological aerosol sprays. It is used in nail lacquers and as a color developer in hair dyes by the cosmetics industry (22), and in acne treatment preparations (23). 

Sulfur has long been known for its properties as a pesticide and a curative agent. Homer spoke of the pest-averting sulfur as far back as 800—1000 BC, Hippocrates (400 Bc) considered sulfur sa an antidote against plague, and Dioscorides (100 ad) used sulfur ointment in dermatology (244). In 1803, the use of a lime—sulfur protective treatment for fmit trees was reported, and in 1850 sulfur dust was used to protect foHage (245). In 1891 sulfur dust was used on soil to control onion smut (246). 

Panthenol is frequently used in ointments and solutions for the treatment of burns, anal fissures, and inflammation of the conjunctiva. The vitamin has to be substituted in patients on total parenteral nutrition and in those who regularly undergo dialysis. Hypervitamin-osis has not been observed for doses up to 5 g/d (22). Furthermore, the administration of pantothenic acid leads to improved surgical wound healing due to its antiinflammatory properties. 

Due to their excellent emulsifying properties, sodium alcohol sulfates are used as emulsifiers for cosmetic creams. In particular, cetylstearyl sulfate in combination with fatty alcohols is used as an emulsifier for ointments. 

To be semisolid, a system must have a three-dimensional structure that is sufficient to impart solidlike character to the undistributed system that is easily broken down and realigned under an applied force. The semisolid systems used pharmaceutically include ointments and solidified w/o emulsion variants thereof, pastes, o/w creams with solidified internal phases, o/w creams with fluid internal phases, gels, and rigid foams. The natures of the underlying structures differ remarkably across all these systems, but all share the property that their structures are easily broken down, rearranged, and reformed. Only to the extent that one understands the structural sources of these systems does one understand them at all. 

Several alternative means of forming hydrocarbon ointments illustrate their structural properties. Ointments can be made by incorporating high melting... 

Topical calcineurin inhibitors (e.g., tacrolimus ointment, pimecrolimus cream) have fungicidal and antiinflammatory properties and can be used for the scalp or face. 

Many attempts to alter the physical properties of neomycin by the formation of various salts have been described. Thus the neomycin salts of the higher fatty acids, such as the stearate, palmitate and myristate3(3 31 were prepared and being water-insoluble were formulated in ointment bases. Similarly, the undecylenate salt has been prepared and processes for its production patented3 33 34 The undecylenate and caprylate salts have been described as being particularly suitable as antimitotic compounds35. 

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