Nutrients Oleic acid

In culture, the human colon carcinoma cell hne Caco-2 spontaneously differentiates at confluency into polarized cells with enterocyte-like characteristics. The principle of this approach consists of following the passage of the compound of interest from the apical or lumen-like sides to the basolateral or lymph-hke sides of Caco-2 cells, thus following the absorption of the compound per se. One obhgate step for fat-soluble nutrients such as carotenoids to cross the intestinal barrier is their incorporation into CMs assembled in the enterocytes. Under normal cell culture conditions, Caco-2 cells are unable to form CMs. When supplemented with taurocholate and oleic acid, Caco-2 cells were reported to assemble and secrete CMs. ... 

Saturated fatty acids or unsaturated fatty acids, such as oleic acid (18 1, n-9), can be synthesized by normal mammalian cells that posses elongation and desaturation enzymes (Rosenthal, 1987). However, the polyunsaturated fatty acids of the n-3 and n-6 group, such as linoleic acid (18 2, n-6) or linolenic acid (18 3, n-3), are essential nutrients for animals because they are precursors for the synthesis of eicosanoid hormones such as prostaglandins (Needleman et al., 1986). 

Dates Phoenix dactylifera L.) are popular in most Middle Eastern countries and serve as a major source of food and nutrients (51, 52). Oil contents and fatty acid profiles of date seeds may vary among individual varieties. Date seeds contained 20-24% total fat (49). Oleic acid was the primary fatty acid in the date seed oil and had a concentration of 43.5 5% of total fatty acids. This was followed by lauric (12 0), myristic (14 0), palmitic (16 0), linoleic (18 2n6), capric (10 0), and stearic (18 0) acids along with trace amounts of other fatty acids (Table 7). Date seed oil may serve as an excellent dietary source of oleic acid with a minor amount of linoleic acid. 

If you ve encountered date pits, you know their usual fate—they are promptly discarded. But wait a nutritional study of date pits has documented their exceptional nutrient density, especially of protein, dietary fiber, and omega oils composed mainly of oleic acid, the same omega-9 monounsaturated fat famous in olive oil. Date pits may offer an inexpensive nutrient and oil source from what is currently a waste material. Simply through extraction or pulp processing of the pits, some future entrepreneur will recover those inedible pits and transform them into useful food products ... 

Abraham, S. Narine, S. S. (2009). Self-assembled nanostructures of oleic acid and their capacity for encapsulation and controlled delivery of nutrients. Journal of Nanoscience and Nanotechnology, 9(11), 6326-34. 

Lin, H. C., Van Citters, G. W., Heimer, F., and Bonorris, G. (2001). Slowing of gastrointestinal transit by oleic acid - A preliminary report of a novel, nutrient-based treatment in humans. Digestive Diseases and Sciences, 46(2), 223-229. 

Definite evidence has recently been found that oleic acid plays a part in the growth requirements of several micro-organisms. Fleming in 1909 (94) observed that the acne bacillus (Corynebacterium acnes), which is difficult to cultivate, grew best in ordinary nutrient agar to which 1-5% oleic acid was added. 

The mammary gland produces milk, which is the major source of nutrients for the breastfed human infant. The fatty acid composition of human milk varies, depending on the diet of the mother. However, long-chain fatty acids predominate, particularly palmitic, oleic, and linoleic acids. Although the amount of fat contained in human milk and cow s milk is similar, cow s milk contains more short- and medium-chain fatty acids and does not contain the long-chain, polyunsaturated fatty acids found in human milk that are important in brain development. 

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