Nucleosides, Nucleotides, and Polynucleotides

Gurzadyan GG, Gorner H (1994) Damage to uracil- and adenine-containing bases, nucleosides, nucleotides and polynucleotides quantum yields on irradiation at 193 and 254 nm. Photochem... 

MISCELLANEOUS COMPOUNDS (including biologically useful reagents, low-molecular-weight bioactive substances, antibiotics, coenzymes, vitamins, lipids, phospholipids, nucleosides, nucleotides and polynucleotides)... 

Infrared spectra of heavy-water solutions have been used to determine the tautomeric forms of nucleosides, nucleotides, and polynucleotides and to study the... 

In order to make quantitative measurements. Miles (1958f)) has determined integrated infrared absorption intensities for some nucleosides, nucleotides, and polynucleotides in DjO solution (Fig. 12.8 and Table 12.2) by application of Ramsay s method I (Ramsay, 1952). When there is a well-resolved band, the application of Ramsay s method encounters no difficulty, but when overlapping bands occur, as in uridine and its derivatives, some uncertainty exists in determining the halfband width of a particular band. (The half-band width is a factor in Ramsay s equation and is defined as, Av, 2 = the width of the band in cm" at half-maximum intensity.) The equation as used by Miles to obtain A, the true integrated absorption intensity... 

Synthesis of nucleotides and nucleosides, nucleotide coenzymes, polynucleotides, and histidine... 

In addition to the enzymes that catalyse the formation of nucleotides and polynucleotides, a large number of catabolic systems exist which operate at all levels of the internucleotide pathways. The ribonucleases and deoxyribonucleases that degrade polynucleotides are probably not significantly involved in purine analogue metabolism, but the enzymes which dephosphorylate nucleoside 5 -monophosphates are known to attack analogue nucleotides and may be of some importance to their in vivo activity. Phosphatases of low specificity are abundant in many tissues [38], particularly the intestine [29]. Purified mammalian 5-nucleotidases hydrolyse only the nucleoside 5 monophosphates [28] and... 

Interaction of Polynucleotides with Nucleosides, Nucleotides, and Purines... 

N-Glycosides. The alcoholic component reacts with the sugar through a NH-group. A-Glycosidic linkages are found in the nucleosides and, thus, in the nucleotides and polynucleotides. 

HPLC resins containing nucleic acid base derivatives were prepared. These resins give excellent complimentary separation of nucleic acid base derivatives, nucleosides, nucleotides, and oligonucleotides. These resins may be useful for the separation of components of nucleic acids and polynucleotides as a specific separation system, while ion-exchange and reverse-phase systems are non-specific separation systems. 

Base Sequence The sequence of purines and pyrimidines in nudeic adds and polynucleotides. It is also called nucleotide or nucleoside sequence. [NIH]... 

As far as we know, no reports are available that summarize our present knowledge of the bacterial nucleotides and nucleosides. This review will deal with the nucleosides and low-molecular nucleotides isolated from bacterial systems, their structure, and the function of some of these substances in synthetic processes (but the biosynthesis of polynucleotides is not included). In addition, the enzymic action of cell-free extracts on nucleosides and low-molecular nucleotides has been considered. 

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