Nitrogen secondary

Enns MW, Cox BJ, Parker JD, Guertin JE. (1998). Confirmatory factor analysis of the Beck anxiety and depression inventories in patients with major depression. J Affective Disord. 47(1-3) 195-200. Erdelmeier CA. (1998). Hyperforin, possibly the major non-nitrogenous secondary metabolite of Hypericum perforatum L. Pharmacopsychiatry. 31(suppl 1) 2-6. 

On the other hand, most alkaloids contain much less nitrogen as a fraction of the total weight than nicotine (Table I), and toxic compounds such as alkaloids are usually found at very low concentrations In the plant (12). Thus, the allocation of nitrogen to nitrogenous secondary compounds can range from substantial to negligible, even with comparable allocations of carbon. 

When a nitrogen-secondary carbon bond is broken in the hydrolysis, the reaction occurs with inversion of configuration as shown by studies of the hydrolysis of the 2r3-diraethylaziridjnealzs and cyclo alksmminee.840... 

Are non-nitrogenous secondary metabolites better taxonomic markers Whereas flavonoids are found in all three subfamilies, and are thus of limited value at the family/tribal level, isoflavones are obviously restricted to the... 

Aromatic hydrocarbons (including benzene), phenols, and phenolic ethers can be cyanated with trichloroacetonitrile, BrCN, or mercury fulminate I (ONC)2. In the case of CI3CCN, the actual attacking entity is probably CI3C C =NH, formed by addition of a proton to the cyano nitrogen. Secondary aromatic amines ArNHR, as well as phenols, can be cyanated in the ortho position with CI3CCN and BCl3. ... 

Alkaloids are nitrogenous secondary metabolites primarily derived from amino acids for both their... 

Erdelmeier CAJ. Hyperforin, possibly the major non-nitrogenous secondary metabolite of Hypericum perforatum L. Pharmacopsychiatry 1998 31 2-6. 

Amines are compounds in which one or more of the hydrogens of ammonia have been replaced by alkyl groups. Smaller amines are characterized by their fishy odors. Fermented shark, for example, a traditional dish in Iceland, smells exactly like trieth-ylamine. There are primary amines, secondary amines, and tertiary amines. The classification depends on how many alkyl groups are bonded to the nitrogen. Primary amines have one alkyl group bonded to the nitrogen, secondary amines have two, and tertiary amines have three. 

Amines are divided into three classes—primary, secondary, and tertiary —depending upon the number of replaced hydrogens in the parent substance ammonia. Primary amines contain two remaining hydrogen atoms attached to the ammonia nitrogen, secondary amines contain one, and tertiary amines have none remaining. 

The AGR has a nitrogen secondary shutdown circuit. The RBMK helium-nitrogen system, however, is used to adjust graphite temperature while keeping an inert atmosphere and does not have a second defensive shutdown role. Some UK graphite reactors have, in addition, a capacity to drop neutron absorbing beads into the core or inject boron dust into the primary gas circuit. 

Dimeric self-assembly via tellurium-nitrogen secondary bonding has been reported in (2-phenylazophenyl-C,A )tellurium(II) thiocyanate (Te- N 3.535 A), 231 [531]. The NCS group is linear (N-C-S 179.3°) and is oriented approximately perpendicular to the tellurium-organic ligand plane (Te-S-C 98.4°). In the bis-(thiocyanato) diphenyltelluriumoxide, (NCSTePh2)20, however, the chain-like... 

Primary amines have one organic group attached to nitrogen, secondary amines have two, and tertiary amines have three. 

Spenser ID (1969) The biosynthesis of alkaloids and of other nitrogenous secondary metabolites. In Florkin M, Stotz EH (eds) Comprehensive biochemistry, vol 20. Elsevier, Amsterdam New York, p 231 and references cited therein Wilson ML, Coscia CJ (1975) Studies on the early stages of Papaver alkaloid biogenesis. J Am Chem Soc 97 431-433... 

Figure 3.1 Distribution of nitrogenous and non-nitrogenous secondary metabolites among photosynthetic organisms (according to Ireland etal.,...

Figure 3.2 illustrates the same distribution for the invertebrates, where it can be seen that there is no correlation between the percentages of nitrogenous secondary metabolites and the position of each phylum on Luden Cuenot s Tree of Life. It is therefore dearly apparent that to find new nitrogenous metabolites, it is better to seek them among tunicates, bryozoans or sponges than among cni-darians, echinoderms, or mollusks. 

Domoic add is one of the rare nitrogenous secondary metabolites encormtered in the diatoms. Isodomoic acids A-F, all isomers of domoic add, have been isolated from the red alga Chondria armata (Chapter 13). For an overall study on ASP and domoic adds, see Daranas, Norte, and Fernandez, 2001 Clayden, Read, and Hebditch, 2005 Kotaki et al (2005), Ramsdell (2007) and Pulido (2008). 

A culture of the freshwater species Poterioochromonas malhamensis permitted the isolation of an inhibitor of the protein tyrosine kinase (PTK) called malhamensilipin A. This derivative of tetracosane (C24) contains six chlorine atoms and an enol sulfate the exact origin of this compound remains unknown however (Chen et al, 1994). Similar derivatives have been isolated from this same species and from another freshwater species, Ochromonas danica (Haines, 1973). Similar structures have been formd in octocorals (see Chapter 20) and toxic mollusks (see Chapter 23). The absence of nitrogenous secondary metabolites has been reported. 

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