New Trends and Strategies in Organic Solid-state Chemistry

New Trends and Strategies in Organic Solid-state Chemistry 

BY L ADDADI, S. ARIEL, M. LAHAV, L LEISEROWITZ, R. POPOVITZ-BIRO, AND C. P. TANG 

Most solid-state reactions investigated up to the late 1960s were observed mainly by accident, without design, a major difficulty being the absence of a general method for producing crystals that have desired characteristics. 

With the development of diffraction techniques, an increasing number of crystal structures has become available. Thus the modes in which various functional groups interact with each other, and the role of these interactions in defining molecular arrangements, are becoming clearer. We now outline some of the properties of molecular architecture in the crystal that can be of value in solid-state chemistry. 

Isomorphism may also be made use of in the engineering of structures. We shall provide examples where one can utilize a known crystal structure composed of molecules that do not embody certain desired functional groups, but whose overall structure fulfils the necessary requirements. To attempt to realize such isomorphism we mark out new molecules that include parts of neighbouring molecules of the original crystal structure. 

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Addadi, L., Ariel, S., Lahav, M., Leiserowitz, L., Popovitz-Biro, R., and Tang, C. P., New trends and strategies in organic solid-state chemistry, in Chemical Physics of Solids and Their SuTfaceSjVoL 8, Roberts, M. W. and Thomas, J. M., Eds., The Royal Society of Chemistry, London, 1980, chap. 7, 202-204. 

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