Solid state chemistry, organic

Gavezzotti, A. Personal communication (1985). See also Gavezzotti, A., Simonetta, M. in Organic Solid State Chemistry (Studies in Organic Chemistry, Vol. 32), Desiraju, G. R. (ed.), Amsterdam—New York, Elsevier 1987, p. 391... 

Cf. e.g. the reviews on Conformational Polymorphism by J. Berstein in Organic Solid State Chemistry (Ed. G. R. Desiraju), Elsevier Amsterdam 1987, p. 471 or by G. R. Desiraju, Crystal Engineering, Material Science Monographs 54, Elsevier, Amsterdam 1989, p. 285. 

J. Bernstein, Conformational polymorphism. In G.R. Desiraju (Ed.), Organic Solid State Chemistry, Elsevier, Amsterdam, 1987, pp. 471-518 Chapter 13. 

Even starting from achiral molecules it is in some systems possible to achieve crystallization in a chiral structure. Perhaps one of the most striking achievements in organic solid-state chemistry has been the trapping of the chirality of such a crystal as the chirality of the stable product of chemical reactions in the crystal. Such asymmetric synthesis has been reviewed (255), and a recent book (256) also provides a thorough discussion of chirality in crystals. The related and fascinating topic of the chemical consequences of the presence of a polar axis in some organic crystals has also been reviewed (257). 

Organic Solid State Chemistry edited by G.R. Deslraju... 

One of the new strategies in organic solid state chemistry is to employ host-guest... 

Toda, F. (1989) Studies of Host-Guest Chemistry. -Fundamentals and Applications of Molecular Recognition and their Development to New Organic Solid State Chemistry-, J. Syn. Org. Chem., Jpn. 47, 1118-1131. 

Desiraju GR (ed) (1987) Organic solid state chemistry. Elsevier, Amsterdam... 

Curtin, D.Y. and Paul, I.C. (1981) Chemical consequences of the polar axis in organic solid-state chemistry. Chemical Reviews, 81, 525-541. 

Desiraju GR, ed. Organic Solid State Chemistry. Elsevier, 1987. 

Jones, W. (1997). Reactivity and crystal design in organic solid state chemistry in Organic Molecular Solids. Properties and Applications (W. Jones, Ed.). CRC Press, Boca Raton, US. 

In spite of the great interest in the phenomenon of polymorphism and of the increased research activity beyond the boundaries of organic solid-state chemistry, it is a fact that only a few molecular compounds possess several crystalline forms, whereas for many other tens of thousands of molecular compounds only one crystalline form is known. In other words, why are there so few molecular crystals polymorphs The often quoted association between number of known forms and the time and energy spent in searching for them put forward by McCrone probably contains the answer to this question. It is probable that if thorough (combinatorial ) crystallization experiments were carried out on any given molecular species or molecular salt, alternative crystalline forms would be found. It is probable but not certain. 

D. Y. Curtin, I. C. Paul, Chemical Consequences of the Polar Axis in Organic Solid-State Chemistry. Chem. Rev. 1981, 81, 525-541. 

Paul, I. C. and Curtin, D. Y. (1987). Gas-solid reactions and polar crystals. In Organic solid state chemistry, Vol. 32, Studies in organic chemistry (ed. G. Desiraju), pp. 331-70. Elsevier, Amsterdam. [237]... 

Thomas, J. M., Morsi, S. E. and Desvergne, J. P. (1977). Topochemical phenomena in organic solid-state chemistry. Arfv. Phys. Org. Chem., 15, 63-151. [235] Thompson, K. C. (2000). Pharmaceutical applications of calorimetric measurements in the new millenium. Thermochim. Acta, 355, 83-7. [250]... 

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