Neurons insulin-like growth factors

Guan J, WiUiams CE, Skinner SJ, Mallard EC, Gluckman PD. 1996. The effects of insulin-like growth factor (IGF)-l, IGF-2, and des-IGF-1 on neuronal loss after hypoxic-ischemic brain injury in adult rats evidence for a role for IGE binding proteins. Endocrinology 137 893-898. 

Hawkes C, Kar S. 2003. Insulin-like growth factor-II/mannose-6-phosphate receptor widespread distribution in neurons of the central nervous system including those expressing cholinergic phenotype. J Comp Neurol 458 113-127. 

McCusker R. H., McCrea K., Zunich S., Dantzer R., Broussard S. R., Johnson R. W., and Kelley K. W. (2006). Insulin-like growth factor-I enhances the biological activity of brain-derived neurotrophic factor on cerebrocortical neurons. J. Neuroimmunol. 179 186-190. 

Zheng W. H. and Quirion R. (2004). Comparative signaling pathways of insulin-like growth factor-1 and brain-derived neurotrophic factor in hippocampal neurons and the role of the PI3 kinase pathway in cell survival. J. Neurochem. 89 844-852. 

Insulin-Like Growth Factor-1 Promotes Neuronal Glucose Utilization During Brain Development and Repair Processes... 

Guan J., Gunn A. J., Sirimanne E. S., et al. (2000) The window of opportunity for neuronal rescue with insulin-like growth factor-1 after hypoxia-ischemia in rats is critically modulated by cerebral temperature during recovery. J. Cereb. Blood Flow Metab. 20,513-519. 

Beck, K. D., Kniisel, B., and Hefti, F., The nature of the trophic action of brain-derived neurotrophic factor, des(l - 3) -insulin-like growth factor-1, and basic fibroblast growth factor on mesencephalic dopaminergic neurons developing in culture, Neuroscience, 52, 855, 1993. 

Dord, S., Kar, S., Quirion, R., 1997a. Insulin-like growth factor I protects and rescues hippocampal neurons against p-amyloid- and human amylin-induced toxicity. Proc. Natl. Acad. Sci. U.S.A. 94,4772-4777. 

D Mello SR, Borodezt K, Soltoff SP. Insulin-like growth factor and potassium depolarization maintain neuronal survival by distinct pathways possible involvement of PI-3-kinase in IGF-1 signaling. J Neurosci 1997 275 661-665. 

Crouch, M.F. and Hendry, I.A. (1991) Co-activation of insulin-like growth factor-I receptors and protein kinase C results in parasympathetic neuronal survival. J. Neurosci. Res. 28 115-120. 

Adamo, M., Werner, H., Farnsworth, W., Roberts, C.T., Rai-zada, M. and Le Roith, D. (1988) Dexamethasone reduces steady state insulin-like growth factor 1 messenger ribonucleic acid levels in rat neuronal and glial cells in primary culture. Endocrinology 123 2565-2570. 

Aizenmann, Y. and de Vellis, J. (1987) Brain neurons develop in a serum and glial free environment effects of transferrin, insulin, insulin-like growth factor 1 and thyroid hormone on neuronal survival, growth and differentiation. Brain Res. 406 32-42. 

Recio-Pinto, E., Rechler, M,M, and Ishii, D.N, (1986) Effects of insulin, insulin-like growth factor II, and nerve growth factor on neurite formation and survival in cultured sympathetic and sensory neurons, J. Neurosci. 6 1211-1219,... 

Roles of insulin-like growth factors in peripheral nerve regeneration and motor neuron survival... 

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