Netherlands Cohort Study

Data concerning gastric cancer are scarce. The prospective Netherlands Cohort Study found no correlation between lutein dietary intake and gastric cancer risk, whereas findings from the Physicians Health Study and the ATBC study reported no effect of P-carotene on gastric cancer incidence. Two case-control studies and three intervention trials (ATBC, CARET, and the Physicians Health Study ) showed no association of P-carotene, lycopene, lutein, zeaxanthin, and P-cryptoxanthin. 

Zeegers, M.P. et al.. Are retinol, vitamin C, vitamin E, folate and carotenoids intake associated with bladder cancer risk Results from the Netherlands Cohort Study, Br. J. Cancer, 85, 977, 2001. 

Schuurman, A.G., van den Brandt, P.A., and Dorant, E. 1999. Association of energy and fat intake with prostate carcinoma risk Results from the Netherlands cohort study. Cancer 86, 1019-1027. 

Voorrips, L., Brants, H., Kardinaal, A., Hiddink, G., and van den Brandt, P. 2002. Intake of conjugated linoleic acid, fat, and other fatty acids in relation to postmenopausal breast cancer The Netherlands cohort study on diet and cancer. Am. J. Clin. Nutr. 76, 873-882. 

An association between black tea consumption and the subsequent risk of colorectal cancer was sought in The Netherlands Cohort Study on Diet and Cancer (Goldbohm et al., 1996). No association was observed between tea consumption and risk of colorectal cancer The risk among tea drinkers in each consumption category was similar to that among nondrinkers. The authors concluded that this study did not support the hypothesis that consumption of black tea protects against fom of the major cancers in humans, and there was no evidence that black tea has a cancer-enhancing effect. 

The association between onion consumption and the incidence of various carcinomas was investigated in the Netherlands Cohort Study. This study revealed that onion consumption is inversely related to the incidence of stomach cancer. However, onion intake failed to reduce the risk of other cancers, such as breast, colon and rectum, and lung carcinomas. " " Results from studies conducted in different provinces in China suggest that the consumption of onion is associated with reduced risk of developing stomach, esophageal, and brain cancers " ... 

Engeland, M. et al., Effects of dietary folate and alcohol intake on promoter methylation in sporadic colorectal cancer The Netherlands Cohort Study on Diet and Cancer, Cancer Res., 63, 3133-3137, 2003. 

Botterweck AA, VerhagenH,GoldbohmRA, Klein]ans J, van den Brandt PA. Intake of butylated hydroxyanisole and butylated hydroxytoluene and stomach cancer risk results from analyses in the Netherlands Cohort Study. Food Chem Toxicol 2000 38 (7) 599-605. 

Voorrips LE, Goldbohm RA, van Poppel G, Sturmans F, Hermus RJ, van den Brandt PA. Vegetable and fruit consumption and risks of colon and rectal cancer in a prospective cohort study the Netherlands Cohort Study on Diet and Cancer. Am J Epidemiol. 2000 152 1081-1092. 

Balder, H.F. et al.. Heme and chlorophyU intake and risk of colorectal cancer in the Netherlands cohort study. Cancer Epidemiol Biomarkers Prev., 15, 717, 2006. 

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