Near-field scanning microscope

NADPH/ NADP+ ratio 776 Naphthalene, resonance energy 299 Nathans, Daniel 84 Natural killer cells 185 Near attack conformation 485 Near-field scanning microscope 130 Neighboring group assistance in displacement reactions 601, 602 Nekoflavin 783 Nematocyst 427 Nematodes 24, 25 Neocarzinostatin 218,224s Neopterin 803... 

Dragnea, B., J. Preusser, W. Schade, S.R. Leone, and W.D. Hinsberg. 1999. Transmission near-field scanning microscope for infrared chemical imaging. J. Appl. Phys. 86 2795-2799. 

While some breakthrough technologies of scanning near-field optical microscope have been developed to overcome the diffractimi limit to increase resolution, these near-field techniques require the distance between the tip and the specimen surface to be in the order of mie to several percents of a wavelength, normally less than 1 pm. However, in nanofluidics and lab-on-a-chip, the channels are mostly enclosed ones and the solid walls are more than 100 pm thick, and hence, the near-field scanning microscopes cannot be appUed to nanofluidics. For lab-on-a-chip appUcatimi, far-field nanoscopy, where the working distance is similar to that of conventional cmifocal microscope, is required for nanofluidics apphcatimis. 

Grober R D, Harris T D, Trautman J K and Betzig E 1994 Design and implementation of a low temperature near-field scanning optical microscope Rev. Sc/. Instrum. 65 626-31... 

Durand Y, Woehl J C, Viellerobe B, Gdhde W and Orrit M 1999 New design of a cryostat-mounted scanning near-field optical microscope for single molecule spectroscopy Rev. Sc/. Instrum. 70 1318-25... 

Gdhde W, Tittel J, Basche T, Brauchle C, Fischer U C and Fuchs H 1997 A low-temperature scanning confocal and near-field optical microscope Rev. Sc/. Instrum. 68 2466-74... 

Near-field scanning optical microscope (NSOM)... 

Nc.ar-Fi ld Scanning Optical Microscope.. The near-field scanning optical microscope (NSOM) should, strictiy speaking, be NSLM for near-field scanning light microscopy because "optical" includes electron optical as well as light optical and NSOM is a light microscope. 

K., Sekkat, Z. and Kawata, S. (1999) Near-field scanning optical microscope using a metallized cantilever tip for nanospectroscopy. Proc. SPIE, 3791,40-48. 

Sugiura, T., Okada, T., Inouye, Y Nakamura, O. and Kawata, S. (1997) Gold-bead scanning near-field optical microscope with laser-force position control. Opt. Lett., 22, 1663-1665. 

Near-field scanning optical microscope (NSOM), 16 501-503 Near-infrared absorbing dyes, 9 341 Near-infrared spectroscopy (nir),... 

Chen, W., and Zhan, Q. 2007. Numerical smdy of an apertureless near field scanning optical microscope probe under radial polarization illumination. Opt. Express 15 4106-11. 

Science is entering into the nanoscale world, and the organization of microscale or nanoscale biomaterial structures on surfaces has been demonstrated and is a subject of extensive research effort.184,851 Single biomaterial molecules have been imaged on surfaces,186 871 and the individual affinity interactions of biomaterials probed at the molecular level.188,891 While the different scanning microscopy techniques provide useful means to image and manipulate biomaterials on surfaces, the use of the near-field scanning optical microscope (NSOM) 9<) in the activation of photoswitchable biomaterials on surfaces should be emphasized specifically. One... 

The concept of the STM has initiated, besides the AFM, a huge family of scanning probe microscopes (SPM), including lateral force microscopes and scanning near field optical microscopes. All these instruments are built up in a very similar way and differ only in the detected interaction between the probe and the sample. We start our discussion with a summary of the common essential parts of all SPMs. 

Fig. 3. Typical setup of a scanning near-field optical microscope. Excitation light is coupled into a single-mode fiber with a metal coated taper at its far end. The light emitted by the aperture illuminates a region of the samples whose size is determined by the aperture diameter and the distance between probe and sample. Light from the interaction region is collect using a conventional optical microscope.

Merritt, G. (1998), A compact near-field scanning optical microscope, Ultramicroscopy, 71(1-4), 183-189. 

Near-field scanning optical microscopy (NSOM) has been developed as a combination of scanning probe microscope and optical microscope in which the spatial resolution is determined by scanning probe microscope resolution while the signals detected are coming from several optical interactions. As a result, NSOM has achieved a higher spatial resolution than that of the classical optical microscopy that uses a conventional lens, which is strictly limited by the diffraction... 

Inouye Y, Kawata S (1994) Near-field scanning optical microscope with a metallic probe tip. Opt Lett 19 159... 

Hayazawa N, Inouye Y, Kawata S (1999) Evanescent field excitation and measurement of dye Fluorescence in a metallic probe near-field scanning optical microscope. J Microsc 194 472... 

Hatano H, Inouye Y, Kawata S (1997) Near-field optical microscope with a multiheight scanning-imaging mode. Opt Lett 22 1532... 

Sands HS, Demangeot F, Bonera E, Webster S, Bennett R, Hayward IP, March F, Smith DA, Batchelder DN (2002) Development of a combined confocal and scanning near-field Raman microscope for deep UV laser excitation. J Raman Spectrosc 33 730... 

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