National Institute of Child Health and Human Development

Contribution No. 3176 from the Gates and Crellin Laboratories of Chemistry, California Institute of Technology, Pasadena, California. This work was supported by grant No. HD-00347 from the National Institute of Child Health and Human Development. 

Section on Growth Factors, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892 Osborn Laboratories of Marine Sciences, New York Aquarium,... 

Ericson JE University of California, Irvine, CA Establish a biomarker of ambient lead (Pb) exposure during prenatal and postnatal development (rats) National Institute of Child Health And Human Development... 

Developmental Pharmacology Branch National Institute of Child Health and Human Development Bethesda, Maryland... 

Stark AR, Carlo WA, Tyson JE, Papile LA, Wright LL, Shankaran S, Donovan EF, Oh W, Bauer CR, Saha S, Poole WK, Stoll BJ. National Institute of Child Health and Human Development Neonatal Research Network. Adverse effects of early dexamethasone in extremely-low-birth-weight infants. National Institute of Child Health and Human Development Neonatal Research Network. N Engl J Med 2001 344(2) 95-101. 

The Cancer and Steroid Hormone Study of the Centers for Disease Control and the National Institute of Child Health and Human Development. The reduction in risk of ovarian cancer associated with oral-contraceptive use. N Engl J Med 1987 316(ll) 650-5. 

Burkman R, Tang M-TC, Malone KE, Marchbanks PA, McDonald JA, Folger SG, Norman SA, Strom BL, Bernstein L, Ursin G, Weiss LK, Daling JR, Simon MS, Spirtas R. Infertility drugs and the risk of breast cancer findings from the National Institute of Child Health and Human Development Women s Contraceptive and Reproductive Experiences Study. Fertil Steril 2003 79 844-851. 

The authors are grateful for support from the Ford Foundation, from N.I.H. (Grant No. R0-1HD07889 from the National Institute of Child Health and Human Development) and from the Medical Research Council of Canada. The patience and care displayed by Ms. 

V. Adrian Parsegian is chief of the Laboratory of Physical and Structural Biology in the National Institute of Child Health and Human Development. He has served as Editor of the Biophysical Journal and President of the Biophysical Society. He is happiest when graduate students come up to him after a lecture and ask hard questions. 

Information about the Pediatric Pharmacology Research Unit (PPRU) can be found by visiting their link through the National Institute of Child Health and Human Development Center for Research for Mothers and Children Endocrine, Nutrition, and Growth Branch, at http //www.nichd. nih.gov/crmc/eng/eng.htm. 

Goepfert AR, Goidenberg RL, Andrews WW, Hauth JC, Mercer B, lams J, et al. The preterm prediction study association between cervical interleukin 6 concentration and spontaneous preterm birth. National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network. Am J Obstet Gynecol 2001 184 483-8. 

The traditional PK study volunteer study in healthy children has proved very hard to set up, because of the attitude of many parents and overviewing independent review boards (IRBs). Even in pediatric patients, the frequency and total volume requirements for samples for conventional PK studies can cause the same refusals. However, there are pediatric research units that specialize in these studies, with minimum needle sticks, minute blood volumes and IRBs sympathetic to the needs of the pediatric community. The National Institute of Child Health and Human Development has set up a network of pediatric pharmacology units , usually in academic regional centers, now... 

Hoffman, H.J. Hunter, J.C. Damns, K. Pakter, J. Peterson, D.R. van Belle, G. Hasselmeyer, E.G. Diphtheria-tetanus-pertussis immunization and sudden infant death Results of the National Institute of Child Health and Human Development Cooperative Epidemiological Study of Sudden Infant Death Syndrome risk factors. Pediatrics 1987, Apr., 79 (4), 598-611. 

NCI = National Cancer Institute NCRR = National Center for Research Resources NICHD = National Institute of Child Health and Human Development NIEHS = National Institute of Environmental Health Sciences NIH = National Institutes of Health USDA= U.S. Department of Agriculture USGS = U.S. Geological Survey... 

---