National Institute for Medical Research

Sir John Warcup Cornforth (1917-2004) was born in Sydney, Australia, and earned his Ph.D. from Oxford University in 1941 working with Sir Robert Robinson. He was on the staff of the National Institute for Medical Research in London from 1946 to 1962, at Shell Research Ltd. (1962-1975), and ultimately at Sussex University (1975-1982). Profoundly deaf since his teens, he worked in constant collaboration with his wife, Rita Harradence. He received the 1975 Nobel Prize in chemistry. 

R. Colin Hughes, National Institute for Medical Research, Mill Hill, London, UK... 

National Institute for Medical Research, London, England. 

David Morgan is a member of the Chemical Ecology Group at Keele University. He was bom in Newfoundland and had his university education there, at Dalhousie University and University of King s College in Halifax, Nova Scotia, and at Oxford. His doctorate thesis was on the lipids of Mycobacterium tuberculosis. He later worked at the National Institute for Medical Research in London, and for Shell Chemical Company and Shell Research under the direction of Sir Robert Robinson, O.M., Nobel Laureate. From 1966 he has been at Keele in Staffordshire as lecturer, senior lecturer, reader, and professor. He discovered the natural pesticide azadirachtin and collaborated with S. V. Ley for its final structure elucidation. He is the author of over 300 papers and reviews, mostly on insect chemistry, editor, and contributor to several volumes and author of the book Biosynthesis in Insects. ... 

The question was raised by the Society s Treasurer, Thomas Merton, that the election of a woman was a break in the traditions of the Society. In response, Henry Dale, the previous Director of the National Institute for Medical Research, commented However much one might wrap it up, the question which we should put could only mean one thing — Do you or do you not wish the Council to continue a discrimination against women candidates which the Law has removed 99... 

Following the completion of her Ph.D. in 1939, Henley accompanied Harington on his move to the National Institute for Medical Research (NIMR) in Hampstead. Her field of specialisation was iodoproteins, and her research on them over the rest of her career was to garner her worldwide fame. The Second World War disrupted her research, as she was seconded to various war-work projects. The last of these, helping the survivors at the liberation of a concentration camp, proved so traumatic that she became a heavy smoker, the probable cause of her death 25 years later. In 1952, she isolated the thyroid hormone, triiodothyronine. The discovery of this new and highly unusual hormone contributed largely to her election as Fellow of the Royal Society only two years later. 

He took an appointment as pharmacologist at the Wellcome Physiological Research Laboratories in 1904 and became director of these laboratories in 1906, working for some six years. In 1914 he was appointed director of the department of biochemistry and pharmacology at the National Institute for Medical Research in London. In 1928 he became the director of this institute, serving until his retirement in 1942, when he became professor of chemistry and a director of the Davy-Faraday Laboratory at the Royal Institution, London. 

Dipaitimento di Chimica, Universita di Napoli Federico II, Via Cinthia, Napoli 1-80126, Italy and National Institute for Medical Research, The Ridgeway, London NV 7 lAA, United Kingdom... 

A standard preparation of thyrocalcitonin, prepared to the salt-fractionation stage by Method 2 above, is available from the Medical Research Council, Department of Biological Standards, National Institute for Medical Research, Mill Hill, London, and is distributed in ampules containing 0.25 MRC unit. When 0.01 MRC unit is injected intravenously into a 150-g rat, it produces a fall of approximately 10% in the plasma calcium after 50 minutes, i.e., this new unit is approximately 100 times larger than that described by Hirsch et al. (H4) and 1000 times larger than that of Baghdiantz et al. (Bl). From the in-... 

This technology was also used to great effect for the production of interferons. Just as one bacterial infection can sometimes provide protection against another, through stimulation of the body s immune system, a similar phenomenon exists with viral infections. This viral interference was first observed by a number of research groups in the 1930s, but an explanation was only provided in 1957. Alick Isaacs and Jean Lindemann, of the National Institute for Medical Research in London, demonstrated that a protein, which they called interferon, was released by cells that had been infected with a virus. This agent then elicited an antiviral response by other cells. 

Studies of the binding of antifolate drugs to the enzyme dihydrofolate reductase (DHFR) carried out by Feeney and Roberts and their colleagues at the National Institute for Medical Research (Mill Hill) provide examples of a diverse range of NMR applications. 

The collaboration between Martin and Synge eventually culminated in a demonstration of partition chromatography to the Biochemical Society at its meeting at the National Institute for Medical Research in London, on June 7, 1941, followed by the publication of their results in Biochemical Journal... 

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