National Cholesterol Education Program guidelines

Monitor patients who are administered sirolimus for hyperlipidemia using laboratory tests. If hyperlipidemia is detected, initiate subsequent interventions such as diet, exercise, and lipid-lowering agents, as outlined by the National Cholesterol Education Program guidelines. 

Bookstein L, Gidding SS, Donovan M, Smith FA. Day-to-day variability of serum cholesterol, triglyceride, and high-density lipoprotein cholesterol levels. Impact on the assessment of risk according to the National Cholesterol Education Program guidelines. Arch Intern Med 1990 150 1653-7. 

Grundy SM, Cleeman JT, Merz CN et al (2004) Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines. Circulation 110 227-239... 

The following modifications were made to the National Cholesterol Education Program treatment guidelines in patients at high or very high risk for IHD-related events ... 

The National Cholesterol Education Program Adult Treatment Panel III guidelines have set the optimal level for low-density lipoprotein (LDL) cholesterol for all adults as less than 100 mg/dL (2.59 mmol/L). 

Insulin resistance has been associated with a number of other cardiovascular risks, including abdominal obesity, hypertension, dyslipidemia, hypercoagulation, and hyperinsulinemia. The clustering of these risk factors has been termed metabolic syndrome. It is estimated that 50% of the United States population older than 60 years of age have metabolic syndrome. The most widely used criteria to define metabolic syndrome were established by the National Cholesterol Education Program Adult Treatment Panel III Guidelines (summarized in Table 40-2). 

Different classification systems are available to estimate the individual risk of presenting a cardiovascular event in the next 10 years. One of the most frequently used is the Framingham score risk, for which there is also software available online (Third Report of the National Cholesterol Education Program 2002), but recently several organizations involved in cardiovascular care have produced guidelines to identify and manage these risk situations (Mosca 2004). 

Third Report of National Cholesterol Education Program (2002) Circulation 106 3143-3421. http //www.nhlbi.nih.gov/guidelines/cholesterol/index.htm... 

Hyperlipidemia The following dosages are from the National Cholesterol Education Program (NCEP) Expert Panel III guidelines ... 

The following treatments guidelines are provided by the National Cholesterol Education Program Expert Panel on Detection, Evaluation and Treatment of High... 

Table 35-1 National Cholesterol Education Program Adult Treatment Guidelines (2001). ...

More specifically, the ATP III guidelines, from the third report of the National Cholesterol Education Program s expert Adult Treatment Panel on Detection, Evaluation,... 

The National Cholesterol Education Program (NCEP)-recommended steps to lower the risk of CAD, collectively referred to as the TLC, are presented in Table 8.4. These guidelines are typically used for higher-risk individuals with elevated plasma cholesterol concentrations, established cardiovascular disease, and more than one major risk factor. The TLC dietary guidelines are relatively stringent, limiting daily total and saturated fat intakes to <30% and 7% of total energy and cholesterol... 

Frolkis, J.R et al.. Physician noncompliance with the 1993 National Cholesterol Education Program (NCEP-ATPII) guidelines. Circulation, 98, 851, 1998. 

Drewnowski, A., Taste preferences and food intake, Annu. Rev. Nutr., 17, 237, 1997. Hsia, J. et al. Compliance with National Cholesterol Education Program dietary and lifestyle guidelines among older women with self-reported hypercholesterolemia. The Women s Health Initiative, Am. J. Med., 113, 384, 2002. 

FDA reviewed the scientific evidence and recommendations of various scientific bodies, including the Institute of Medicine, National Academies of Science, an expert panel for the National Cholesterol Education Program, and the Advisory Committee on the Dietary Guidelines for Americans 2000. On July 9, 2003, the FDA issued a regulation requiring manufacturers to list trans fatty acids on the Nutrition Facts panel of the labels of foods and some dietary supplements. The new requirement will mean that manufacturers of most conventional foods and some dietary supplements will have to list in the Nutrition Facts panel the trans fat content of the product, in addition to the information about its overall fat content and saturated fat content. Dietary supplement manufacturers will need to list trans fat, as well as saturated fat and cholesterol, on the Supplement Facts panel when their products contain more than trace amounts (0.5 g) of trans fat. Examples of dietary supplements that may contain trans fat are energy and nutrition bars. 

Sempos, C.T. Cleeman, J.I. Carroll, M.D. Johnson, C.L. Bachorik, P.S. Gordon, D.J. Burt, V.L. Briefel, R.R. Brown, C.D. Lippel, K. Rifkind, B.M. Prevalence of high blood cholesterol among U.S. adults An update based on guidelines from the second report of the National Cholesterol Education Program adult treatment panel. JAMA, J. Am. Med. Assoc. 1993, 269 (23), 3009-3014. 

S. M. Grundy, J. I. Cleeman, C. N. Merz, H. B. Brewer, Jr., L. T. Clark, D. B. Hunninghake, R. C. Pasternak, S. C. Smith, Jr., and N. J. Stone, Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines. Arterioscler Thromb Vase Biol 24 el49-el61 (2004). 

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