Framingham risk score

Different classification systems are available to estimate the individual risk of presenting a cardiovascular event in the next 10 years. One of the most frequently used is the Framingham score risk, for which there is also software available online (Third Report of the National Cholesterol Education Program 2002), but recently several organizations involved in cardiovascular care have produced guidelines to identify and manage these risk situations (Mosca 2004). 

TABLE 9-5. CHD Risk Factors and Needed Risk Factors for Framingham Score Calculation... 

Robust epidemiologic evidence has identified an inverse relationship between HDL-cholesterol levels and CHD risk. Indeed, HDL-cholesterol is included in the Framingham CHD risk prediction scores (29). HDL-cholesterol protects against... 

Greenland P, LaBree L, Azen SP, Doherty TM, Detrano RC (2004) Coronary artery calcimn score combined with Framingham score for risk prediction in asymptomatic individuals. JAMA 291 210-215... 

Mahoney L.T. et al.. Usefulness of the Framingham risk score and body mass index to predict early coronary artery calcium in young adults (Muscatine Study), Am. J. Cardiol, 88, 509, 2001. 

Wannamethee SG, Shaper AG, Lennon L, Morris RW. Metabolic syndrome vs. Framingham risk score for prediction of coronary heart disease, stroke, and type 2 diabetes mellitus. Arch. Int. Med. 2005 165 2644-2650. 

Since hsCRP values minimally correlate with Upid concentrations and lipid parameters account for <3% to 5% of the variance in hsCRP measurement, the measurement of hsCRP does not replace but instead complements the evaluation of lipids and other classical CHD risk factors in primary prevention settings. Data from the WHS demonstrated that hsCRP adds prognostic information not only at all levels of the risk defined by current LDL cut points of the NCEP but also at ah levels of the risk specified by the Framingham risk score algorithm. ... 

---