Nanomedicine nanoparticles

Keywords Drug delivery Nanomedicine Nanoparticle PEGylated drug PEGylation... 

Nanoelectronics Nanogap Fabrication Nanomaterials Nanomedicine Nanoparticle... 

By changing the ultrasound power, changes in the mesoporosity of ZnO nanoparticles (average pore sizes from 2.5 to 14.3 nm) have been observed. In addition to the changes in mesoporosity, changes in the morphology have also been noted [13]. Recently, Jia et al. [14] have used sonochemistry and prepared hollow ZnO microspheres with diameter 500 nm assembled by nanoparticles using carbon spheres as template. Such specific structure of hollow spheres has applications in nanoelectronics, nanophotonics and nanomedicine. 

I. Roy, T. Y. Ohulchanskyy, D. J. Bharali, H. E. Pudavar, R. A. Mistretta, N. Kaur and P. N. Prasad, Optical tracking of organically modified silica nanoparticles as DNA carriers a nonviral, nanomedicine approach for gene delivery, Proc. Natl. Acad. Sci. USA, 2005, 102, 279. 

Bums AA, Vider J, Ow H, Herz E, Penate-Medina O, Baumgart M, Larson SM, Wiesner U, Bradbury M (2009) Fluorescent silica nanoparticles with efficient urinary excretion for nanomedicine. Nano Lett 9 442-448... 

Son SJ, Bai X, Lee SB (2007a) Inorganic hollow nanoparticles and nanotubes in nanomedicine. Part 1. Drug/gene delivery applications. Drug Discov Today 12 650-656. 

Huang X, Jain PK, El-Sayed IH, El-Sayed AM. Gold nanoparticles Interesting optical properties and recent applications in cancer diagnostics and therapy. Nanomedicine 2007 2 681-93. 

Bhattarai SR, Kim SY, Jang KY, Lee KC, Yi HK, Lee DY, Kim HY, Hwang PH (2008) N-Hexanoyl chitosan-stabilized magnetic nanoparticles enhancement of adenoviral-mediated gene expression both in vitro and in vivo. Nanomedicine 4 146-154... 

McCarthy J, Gong X, NahirneyD etal (2011) Polystyrene nanoparticles activate ion transport in human airway epithelial cells. Int J Nanomedicine 6 1343-1356... 

Cui W, Li J, Zhang Y, Rong H, Lu W, Jiang L (2012) Effects of aggregation and the surface properties of gold nanoparticles on cytotoxicity and cell growth. Nanomedicine 8(l) 46-53... 

Scheme 1 illustrates the domains of nanomedicine. These can be considered to cover nanodevices, nanocarriers [which include nature s own vehicles such as low-density lipoprotein (LDL) particles (10,11)], virases, and transmitter vesicles. Nanotoxicology is of course a primary consideration, but is outside the scope of this chapter. Diagnostic devices and imaging techniques employing nanoparticles are being developed rapidly. 

Manchester M. Targeted therapy using virus-based nanoparticles (VNPs). Nanomedicine 2006 2 294. 

Darton NJ, Hallmark B, Huan X, et al. The in-flow capture of superparamagnetic nanoparticles for targeted therapeutics. Nanomedicine 2008 4 19-29. 

Pridgen EM, Langer R, Farokhzad OC (2007) Biodegradable, polymeric nanoparticle delivery systems for cancer therapy. Nanomedicine 2 669-680 Rzaev ZMO, Dincer S, Piskin E (2007) Functional copolymers of N-isopropylacrylamide for bioengineering applications. Prog Polym Sci 32 534—595 Schild HG (1992) Poly (N-Isopropylacrylamide) - experiment, theory and application. Prog Polym Sci 17 163-249... 

Nahar, M., Mishra, D., Dubey, V., and Jain, N.K. Development, characterization, and toxicity evaluation of amphotericin B-loaded gelatin nanoparticles. Nanomedicine 4 252-261, 2008. 

Rhyner MN et al. (2006) Quantum dots and multifunctional nanoparticles New contrast agents for tumor imaging. Nanomedicine. 1 209-217. 

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