Multiple sclerosis neurological symptoms

Levin L.I., et al., Temporal relationship between elevation of Epstein-Barr virus antibody titers and initial onset of neurologic symptoms in multiple sclerosis, JAMA, 293, 2496, 2005. 

Neurologic events Infliximab and other agents that inhibit TNF have been associated in rare cases with optic neuritis, seizure, and new onset or exacerbation of clinical symptoms or radiographic evidence of CNS demyelinating disorders, including multiple sclerosis and CNS manifestations of systemic vasculitis. Exercise caution in considering the use of infliximab in patients with pre-existing or... 

Another problem facing the diagnosis of depression or mania is the fact that other medical conditions can cause similar symptoms. Among them are illnesses such as thyroid diseases, infectious diseases (the flu), cancers of the central nervous system, neurological disorders (multiple sclerosis), blood diseases, and even some reactions to metal toxicity. 

Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS) that affects between 250,000 and 350,000 persons in the United States. It is one of the major causes of neurologic disability in young and middle-aged adults. The term multiple sclerosis refers to two characteristics of the disease the numerous affected areas of the brain and spinal cord producing multiple neurologic symptoms that accrue over time and the characteristic plaques or sclerosed areas that are the hallmark of the disease. 

UI may present in the setting of concurrent, seemingly unrelated illnesses. New-onset UI may be the initial manifestation of certain systemic illnesses such as diabetes meUitus, metastatic malignancies, multiple sclerosis, and other neurologic illnesses. Central nervous system disease, or injury above the level of the pons, generally results in symptoms of bladder overactivity and UUI. Spinal cord injury or disease may manifest as bladder overactivity and UUI or as overflow incontinence, depending on the spinal level and completeness of the injury or disease. 

MnHiple sclerosis Lithium was effective in a mouse model of experimental autoimmune encephalomyelitis (a model of multiple sclerosis). It reduced neurological symptoms if administered both before and after induction of the illness ami the animals rapidly relapsed if lithium was withdrawn [34 ]. 

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