Mouse Genome Database

MGDB Mouse Genome Database http //www. informatics.jax.org... 

Blake, J.A., Eppig, J.T., Bulk C.J. et al.. The Mouse Genome Database (MGD) updates and enhancements. Nucleic Acids Res., 34, D562-D567 (2006). 

For some model organisms, cDNA resources are already prepared and shared in the research community. Thus, when there is a need to study about functional genomics of a model organism, a search for appropriate cDNA resources open to the public should be made first. These lines of information may be found in genomic databases and/or Web sites of publicly funded genome projects. For example, human and mouse ORF clones are available from the ORFeome collaboration (http //www.orfeomecollaboration.org/html/index.shtml). 

Some mouse strains may develop a metabolic syndromelike phenotype or have pathologically high reward-related phenotype (see Mouse Phenome Project or Mouse Genome Informatix database for these phenotypes of interest e.g., metabolic syndrome-like phenotypes in NeilltmlRsld/NeilltmlRsld mice). Thus, their sucrose consumption may be abnormally affected and alternative methods of depression testing or other mouse strains may be required. 

Certain strains of mice may be less inclined to explore the test environment, such as mice with anxiety- or depressionlike phenotypes (see Mouse Phenome and Mouse Genome Informatics Databases for details). Allow a longer acclimation and/or test time (e.g., 10 or 15 min) to reduce this... 

The Sequence Retrieval System (SRS [19]), initially developed at EMBL and the European Bioinformatics Institute, uses an interesting approach by combining the features of data warehouses and federated database systems. SRS is on the one hand heavily indexing locally stored genomic flat file databases and, on the other hand, it allows one to query DBMS on different sites. An example for a federated approach is the Mouse Federated Database of the Comparative Mouse Genomics Centers Consortium (http //www.niehs.nih. gov/cmgcc/dbmouse.htm). 

WICGR s mouse mapping project and the University of Wisconsin s Rat Genome Database (RGD Steen et al., 1999) have aligned the GL and RH maps for the... 

Bovine Genome Database MCW Rat-Mouse-Human Single-chromosome/regional... 

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