Molecular, generally

The same role that H plays in the theory of complex atoms may be expected for Hj as the prototype from which to generalize electron configurations of complex molecules. The molecular generalization must clearly... 

Harayama, S., Rekik, M., Wasserfallen, A. Bairoch, A. (1987). Evolutionary relationship between catabolic pathways for aromatics conservation of gene order and nucleotide sequences for catechol oxidation genes of pWWO and NAH7 plasmids. Molecular General Genetics, 210, 241-7. 

Molecular Generality of SERS Outer- and Inner-sphere Adsorbates... 

Servos, J., Haase, E., and Brendel, M. (1993) Gene SNQ2 of Saccharomyces cerevisiae, which confers resistance to 4-nitroquinoline-N-oxide and other chemicals, encodes a 169 kDa protein homologous to ATP-dependent permeases. Molecular General Genetics, 236, 214-218. 

Carvajal, E., van den Hazel, H.B., Cybularz-Kolaczkowska, A., Balzi, E., and Goffeau, A. (1997) Molecular and phenotypic characterization of yeast PDR 3 mutants that show hyperactive transcription of various ABC multidrug transporter genes. Molecular General Genetics, 256, 406-41 5. 

Fling, M.E., Kopf, J., Tamarkin, A., Gorman, J.A., Smith, H.A., and Koltin, Y. (1991) Analysis of a Candida albicans gene that encodes a novel mechanism for resistance to benomyl and methotrexate. Molecular General Genetics, 227, 318-329. 

An important concept in chemical kinetics is molecularity of a reaction or the number of particles (molecules, atoms, ions, radicals) participating in it. Most common are bimolecular reactions, unimolecular reactions being also encountered. In very rare cases termolecular reactions may be observed as well. Reactions of higher molecularity are unknown, which is due to a very low probability of a simultaneous interaction of a larger number of molecules. Consequently, our further considerations will be confined to the examination of uni- and bimolecular reactions. On the other hand, the reactions of a termolecular character, whose kinetic equations have a number of interesting properties, are sometimes considered. As will appear, a termolecular reaction may be approximately modelled by means of a few bimolecular reactions. For an elementary reaction its molecularity is by definition equal to the order whereas for a complex reaction the molecularity generally has no relation whatsoever to the reaction order or the stoichiometry. 

As expected from the low hydrogen-bonding ability of sulphur, attempts to observe either intra- or inter-molecular general acid catalysis in the hydrolysis of hemithioacetals have met with little success. The only convincing example is compound LXXIV, in which acid catalysis is concerted with nucleophihc attack by the second carboxylate and contributes a rate enhancement of about 10 [177]. 

As an observation, the correlation energy (4.473) supports also the immediate not spherically (molecular) generalization ... 

In aspirin, the acid catalysis is enhanced by the presence of an intra-molecular hydrogen bond. The H-bond in the salicylate anion is worth 17-21 kJ mol and raises the of the phenolic OH to 13. Other molecular models showed that EMs for intra-molecular general acid-base catalysis can be at least 10" M, if favourable intra-molecular H-bonds are formed [10]. This is also the factor that separates the typical pre-exponential factor of a bimolecular reaction in solution, 10 M sec from that of an intra-molecular reaction between the hydrogen-bonded reactants, 10 sec The basis for this change has been discussed in the context of the intersecting-state model (ISM) applications to proton transfers... 

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