Microfluidic Systems Packaging

Microfluidic component assembly Microfluidic integration Microfluidic systems assembly Microfluidic systems packaging... 

Krulevitch, P., Benett, W., Hamilton, J., Maghribi, M., Rose, K., Polymer-based packaging platform for hybrid microfluidic systems. Biomed. Microdevices 2002, 4(4), 301-308. 

Another relevant issue for sensors is packaging. In particular, for chemical sensors designed for working in solution, it is necessary to prevent the solution from any contact with the semiconductor layer (if this is not the sensitive layer of the device). Microfluidic systems [35,36] coupled with the sensor s active areas offer a valid solution to this problem because they allow the flow of the solution to the active area to be controlled and channeled, without compromising the semiconductor layer. For pressure/strain sensors the packaging should not compromise the mechanical flexibility of the whole structure. 

Morrissey A, Kelly J, Alderman J (1997) 3D packaging of a microfluidic system with sensory applications. Proc SPIE 3224 161-168... 

Li S, Chen S (2003) Polydimethylsiloxane fluidic interconnects for microfluidic systems. IEEE Trans Adv Packag 26(3) 242-247... 

Han KH, Frazier AB (2005) Reliability aspects of packaging and integration technology for microfluidic systems. IEEE Trans Device Mater Reliab 5(3) 452- 57... 

As previously mentioned, the analysis of microfluidic systems can be rather difficult for a variety of reasons. The direct implementation of the Navier-Stokes equations toward surface-directed microfluidic systems requires careful attention when considering the advection of the free surface and the associated curvature of this surface. Consequently, sophisticated computational fluid dynamics software packages are required for a comprehensive three-dimensional analysis of the fluid transport within surface-directed microfluidic devices. However, a time-consuming comprehensive analysis may be beyond the requirements of designing and manufacturing functional surface-directed microfluidic platforms. Consequently, empirical approximations and scaling arguments are commonly used in the characterization of microfluidic physics. 

This concept, however, does not imply that every microfluidic platform needs to provide a complete set of all the unit operations listed in Table 1. It is much more important that the different elements are connectable, ideally in a monolithically integrated way or at least by a well defined, ready-to-use interconnection and packaging process. Therefore at least one validated fabrication technology is required to realize complete systems from the individual elements within a microfluidic platform. 

In this case the variation in the surface properties is also expressed through the slip boundary condition. A numerical technique is typically required to capture a solution however, nearly all commercial CFD packages provide this functionality. The advantage of the above system is of course that it allows one to describe 2D and 3D velocity fields in microfluidic devices which commonly have channel lengths on the order of several centimeters without having to worry about resolving the solution on the spatial scale of the double layer (which can be seven orders of magnitude smaller). 

Customer-based production of formulations (besides emulsions) based on a package system with an incorporated static micromixer [19] Vesicle formation in microfluidic stmctures [21]... 

The system, highlights Motorola s expertise in miniaturization, microfluidics, energy conversion systems, electronic packaging and interface. Making a practical 1 W fuel cell system (Fig. 14) requires not only a small-sized fuel cell stack, but also miniature, low-power peripheral components. 

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