Methanol, reaction with fluorinated

As in the case of the fluorination of alkenes in methanol, reaction with 1,3-dienes depends strongly on the catalyst used, and five products were formed by reaction of 2,3-dimethyl-1,3-butadiene when hydrogen fluoride or boron trifluoride were used as catalysts83 (Scheme 27). 

The small effect on reaction rates of the addition of crown ethers to the lower alcohols was also observed in the reaction of potassium acetate with 1-bromobutane in ethanol (Hirao et al., 1978a,b). The displacement of fluorine in either o-nitro- or p-nitro-fluorobenzene by a methoxy group, by reaction with potassium methoxide in methanol was hardly influenced by the presence of dicyclohexyl-18-crown-6 (Del Cima et al., 1973). Mariani et al. (1978), too,... 

Explosive reaction with sodium -I-methanol or sodium methoxide + methanol. Mixtures with sodium or potassium are impact-sensitive explosives. Reacts violently with acetone + alkah (e.g., sodium hydroxide, potassium hydroxide, or calcium hydroxide), Al, disilane, Li, Mg, methanol + alkah, nitrogen tetroxide, perchloric acid + phosphorus pentoxide, potassium-tert-butoxide, sodium methylate, NaK. Incompatible with dinitrogen tetraoxide, fluorine, metals, or trhsopropylphosphine. Nonflammable. When heated to decomposition it emits toxic fumes of CT. 

Violent reactions with ammonium salts, chlorate salts, beryllium fluoride, boron diiodophosphide, carbon tetrachloride + methanol, 1,1,1-trichloroethane, 1,2-dibromoethane, halogens or interhalogens (e.g., fluorine, chlorine, bromine, iodine vapor, chlorine trifluoride, iodine heptafluoride), hydrogen iodide, metal oxides + heat (e.g., beryllium oxide, cadmium oxide, copper oxide, mercury oxide, molybdenum oxide, tin oxide, zinc oxide), nitrogen (when ignited), silicon dioxide powder + heat, polytetrafluoroethylene powder + heat. 

An oxidizer. The liquid is a sensitive explosive. Explosive reaction with carbon disulfide (when ignited), methanol (when ignited), pentacarbonyl iron (at 50°C), phosphine + oxygen, sodium diphenylketyl, dichlorine oxide, fluorine, nitrogen trichloride, ozone, perchloryl fluoride (at 100-300°C), vinyl chloride. Reacts to form explosive products with dienes (e.g., 1,3-butadiene, cyclopentadiene, propadiene). 

Trifluoromethyl hypofluorite, CF3OF, is formed by the reaction of fluorine in excess with carbon monoxide, carbon dioxide, methanol, or other compounds containing both carbon and oxygen. In the procedure described below, carbon monoxide first reacts with an excess of fluorine to give largely carbonyl fluoride. The mixture is then passed through a hot tube where nearly all of the carbonyl fluoride reacts with fluorine to give trifluoromethyl hypofluorite. It is desirable to use somewhat more than two volumes of fluorine per volume of carbon monoxide. If this is not done, much perfluorodimethyl peroxide [bis(trifluoromethyl) peroxide] is formed by the combination of carbonyl fluoride with tr fluoromethyl hypofluorite by the reaction ... 

In this way, TS3 may play an important role in the reaction mechanism by increasing the yield of the CH30 radicals. In consequence, part of the methoxy radicals are also formed by attack of the fluorine atom at the methyl-side. This may explain the anomalously high value of the methoxy branching ratio observed experimentally54,55 for the reaction of methanol with fluorine. 

The rate constants for the CH3OH + Cl reaction system were derived by Jodkowski et al.30 using the same method which was first applied to describe the kinetics of the reaction of methanol with fluorine atoms.29 The rate constant calculated for the formation of hydroxymethyl radicals kCi(CH2OH) can be expressed in the temperature range 300 - 1000 K as... 

ANILINE (62-53-3) Combustible liquid (flash point 158°F/70°C). Unless inhibited (usually by methanol), readily able to polymerize. Violent reaction, including the possibility of fire, explosion, and the formation of heat- or shock-sensitive compounds may result from contact with acetic anhydride, benzene diazonium-2-carboxylate, aldehydes, alkalis, benzenamine hydrochloride, boron trichloride, l-bromo-2,5-pyrrolidinedione, chlorosulfonic acid, dibenzoyl peroxide, fluorine nitrate, halogens, hydrogen peroxide, isocyanates, oleum, oxidizers, organic anhydrides, ozone, perchloryl fluoride, perchromates, potassium peroxide, P-propiolactone, sodium peroxide, strong acids, trichloromelamine. Strong reaction with toluene diisocyanate. Reacts with alkaline earth and alkali metals. Attacks some plastics, rubber, and coatings. Incompatible with copper and copper alloys. 

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