Mediterranean Intensive Oxidant Study MINOS

Szulc et al. (2005) reported that skeletal muscle mass was correlated positively with bone mineral content and bone mineral density in the Mediterranean Intensive Oxidant Study (MINOS). MINOS was a prospective study of osteoporosis and its determinants that showed that men with the least skeletal mass also had increased risks of falls due to impaired static and dynamic balance. The relative importance of muscle compared with hormonal and other nutritional effects on bone health may be argued in the MINOS study because factors such as dietary protein, insulin growth factor, and testosterone also affect bone directly, but chronically low muscle mass may provide a visible indicator of bone mass and bone density risk. Osteopenia and osteoporosis are seen as problems in elderly people. In countries with shortened life spans, bone health issues may go unnoticed. 

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