Medical adhesive

For instance, in 1996, 3M company announced a breakthrough in the process for making medical adhesive tapes, a process that reduces energy consumption by 77 percent. The new process also cuts solvent use by 2.4 million pounds, lowers manufacturing costs, and cuts mannfacturing cycle time by 25 percent. The proprietary process took researchers nine years from conception through final implementation. 

Himol Nippon Petrochemicals Medical adhesive material, chewing gum base ingredient... 

Publications on other classes of medical adhesives are rather scarce and incomplete. Past investigations mainly concerned biological aspect, while chemical relationships are treated rather empirically and are reduced to finding optimum mixing ratios. 

The question arises what sections of living tissue should the development of medical adhesives be based on According to our opinion, the optimum adhesion is attained with surfaces characterized by high surface energy. Hence, it is necessary... 

It is impossible to develop a versatile adhesive for all kinds of living tissues, as these differ in their physico-chemical characteristics, functions, rate of regenerative processes, type and degree of saturation with enzymes, etc. It will be necessary in the near future to synthesize and investigate several types of medical adhesives. 

Lipatova, T. E., Pkhakadze, G. A. Medical adhesives. Kiev, Naukova Dumka 1979... 

Figure 4.2 Structure of silicones (a) silicone fluid (Dow Coming 360 Medical Fluid) (b) silicone foam elastomer (c) silicone elastomer (vulcanized Silastic 382 Medicalgrade Elastomer) and (d) silicone elastomer (vulcanized Silastic Medical Adhesive Type A)...

This section focuses on adhesives that are used for the assembly of medical devices. In medical device assembly, the primary substrates are plastics, elastomers, and metals. The total medical adhesive market is much larger since it encompasses a broader definition of products. For example, medical adhesives can be used for bonding human tissue, transdermal drug delivery systems, dental restoration, and wound care in addition to medical device assembly. 

Autoclave sterilization is one of the most difficult common sterilization environments for a medical adhesive, and it is commonly used in hospitals and health care facilities for reusable devices. Autoclaves sterilize with high-pressure steam. Temperatures inside the sterilization chamber typically can reach 130°C with pressures above ambient. Certain adhesive systems, such as polyurethanes, may show hydrolytic degradation in such environments especially after multiple cycles. Epoxies perform the best under multiple autoclave exposures. However, on certain substrates, light-cured acrylics and cyanoacrylates will also perform fairly well. 

In this section, two basic conditions for medical adhesives, adhesive properties and toxicity, are discussed. Table 1 summarizes the common medical PSAs and their adhesive properties. Adhesives, in general. 

In addition, for medical adhesives, safety is another necessary condition. Regarding the skin toxicity of PSA, three primary factors can be considered ... 

Poly-1.4 cw-isoprene is the main component of natural rubber. Natural rubber was most generally used for the earliest medical adhesives due to its excellent adhesive properties and relatively low cost. 

In many cases of drug-in-adhesive manufacturing, the medicated adhesive is first coated on the release liner. 

Focus Reports, short reports on specific aspects of an industry, and complete market reports. Industry report categories include life sciences and biotechnology and medical and pharmaceutical products. Recent titles include Freedonia Focus on Medical Equipment, Cosmetic Surgery Products to 2007, Drug Delivery Systems to 2007, and Medical Adhesives and Sealants to 2007. 

TECHNOMIC PUBLISHING COMPANY 851 New Holland Avenue, Lancaster PA 17604, (717) 291-5609. A variety of conferences covering adhesives, polyurethanes, pressure sensitive adhesives, medical adhesives, and other related topics. 

E.J. Beckman, M. Buckley, S. Anarwal, J. Zhang, Medical adhesive [106] and methods of tissue adhesion, US7264823, 2007. 

R.L. Strausberg, R.P. Link, Protein-based medical adhesives. Trends Biotechnol. 8 (1990) 53-57. 

The cyanaciylate adhesives Eastman (USA), Aron-Alfa (Japan), Kanokonlit (Bulgaria), and MK (CIS) are widely used in medicine, but they have disadvantages decrease of adhesive properties with excess moisture, insufficient film elasticity, comparatively high histo-toxicity, and non-imiversal apphcability as medical adhesives. 

The polyurethane adhesive KL-3 developed by us does not have any topical or systemic toxic effects. Its polymeric film is porous and of high elasticity, and the highly developed surface of the polymer facilitates rapid healing. KL-3 combines the properties of a medical adhesive and of a filling material. Its use is especially indicated when it is necessary to seal tissue defects of considerable size or for closing pathological cavities. 

Response of tissues to KL-3 adhesive. The use of medical adhesives on organs and tissues represents a reliable methodology that allows amelioration of the traumatic consequences of surgical operations. 

WilkoffBE, BelottPH, Love CJ et al (2005) Improved extraction of ePTEE and medical adhesive modified defibrillation leads from the coronary sinus and great cardiac vein. Pacing Clin Electrophysiol 28(3) 205-211... 

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