Matricaria chamomilla, effect

Kupfersztain C, Rotem C, Fagot R, Kaplan B. The immediate effect of natural plant extract, Angelica sinensis and Matricaria chamomilla (Climex) for the treatment of hot flushes during menopause. A preliminary report. Clin Exp Obstet Gynecol 2003 30(4) 203-6. 

Matricaria chamomilla L. -camomila Nervous disturbances Flower (infusion) Afro-Brazilians (Northeast Brazil) [45,46] Flavonoids [104,105] essential oil [106] acylglycerols, linoleic and linolenic acids [107] coumarins [108,109] sesquiterpene lactone [110] inhibits both development of morphine dependence and expression of abstinence syndrome [255,256] anxiolytic effect [257] sedative as well as spasmolytic effects [258]... 

It has been observed by this author that the adaptability of an essential oil bearing plant to a dry habitat (xerophyte) or an environment that is neither too wet or too dry (mesophyte) has a profound effect upon the influence of water stress and intake on the oil yield. Fop example, xerophytic plants such as Coriandrum sativum, Salvia sclarea, Lavandula vera, Matricaria chamomilla, etc. produce an increased oil yield under moisture stress. In contrast, mesophytic plants such as Carum carvi, Levisticum officinale, Anethum graveolens, Ocimum basilicum etc. produce a decreased oil yield under moisture stress. They require a... 

Acute dermatitis was induced by croton oil, arachidonic acid, phenol, and capsaicin. The dermatitis was treated with a-bisabolol. The EO compound showed good anti in ammatory activity (Leite et al., 2011). (-)-a-Bisabolol is a sesquiterpene alcohol and the main compound of the EO of Matricaria chamomilla L. (Asteraceae). It was evaluated for its anti-in ammatory activity using carrageenan-induced mouse paw edema. a-Bisabolol was able to reduce the paw edema at concentrations of—100 or 200 mg/kg—at pre treatment and so did indomethacin, the positive control. It also had sign cant reduction effect in edema induced by dextran. Rat treatment with sesquiterpene alcohol (100 and 200 mg/kg) showed a sign cant decrease of leukocyte migration on carrageenan-induced peritonitis. The level of TNE-a in the peritoneal uid was de nitely reduced in rats when treated with a-bisabolol (Rocha et al., 2011). 

Telekin from the roots of Telekia speciosa, helenin from the roots of Inula helenium L., and sesquiterpene alcohol ledol from the aerial parts of Ledum palustre L. show cytotoxicity [41]. Bisabolol, a nontoxic sesquiterpene alcohol, was isolated from Matricaria chamomilla, Carthamus lanatus, and Matricaria recutita and exhibits a cytotoxic apoptosis-inducing effect [42] against human glioblastoma and pancreatic carcinoma cell lines. 

Alcoholic extracts of Carvi fructus, Foeniculi fructus and Matricariae flos (chamomillae flos) show a clear spasmolytic effect (but not the essential oils ) which depends on other ingredients, like flavones. 

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