Matricariae flos

Normal-phase TLC using a silica stationary phase was employed for the optimization of the separation of flavonoid content of Matricariae flos (Chamomilla recutita L. Rauschert). Air-dried and powdered plant material was extracted by refluxing for 10 min with methanol. The suspension was filtered, evaporated and the residue was redissolved in methanol. The mobile phases included in the experiments were 1 = ethyl acetate-methylethylketone-formic acid-water (50 30 10 10, v/v) 2 = ethyl acetate-methanol-water (75 15 10 v/v) 3 = ethyl acetate-formic acid-water (80 10 10, v/v) 4 = ethyl acetate-formic acid-water (100 20 30, v/v) 5 = ethyl acetate-formic acid-acetic acid-water (100 11 11 27, v/v) 6 = n-butanol-acetic acid-water (66 17 17, v/v) 7 = ethyl acetate-methanol-formic acid-water (75 10 5 10, v/v) 8 = ethyl acetate-acetic acid-water (80 10 10, v/v). Development was carried out in the linear ascending mode at... 

M. Medic-Saric, G. Stanic and I. Bosnjak, The use of information theory and numerical taxonomy methods for evaluating the quality of thin-layer chromatographic separations of flavonoid constituents of matricariae flos. Pharmazie 56 (2001) 156-159. 

Alcoholic extracts of Carvi fructus, Foeniculi fructus and Matricariae flos (chamomillae flos) show a clear spasmolytic effect (but not the essential oils ) which depends on other ingredients, like flavones. 

Matricariae flos Essential oils with sesquiterpenes Drug sample 1 Matricariae flos (steam distillate/5 il)... 

Fig. 21 Official Matricariae flos aetheroleum (1) is characterized by the following zones ...

Anthemidis flos (1) is characterized by prominent grey-violet ester zones at R, 0.8-0.9 (e.g. butylangelat) and a blue zone at R, 0.2 in the range of linalool (Tl). The drug is sometimes used as a substitute for Matricariae flos. 

Chamomillae flos Camomile flowers Matricaria recutita (L.) Chamomilla recutita (L.) RAlJSCHEirr Asteraceae... 

Monosaccharides rhamnose, xylose, glucose, arabinose, galactose, glucuronic acid, galacturonic acid Derivatization 4-aminobenzoic acid ethyl ester D UV A=305nm C Fused silica (72 cm x 50 im i.d.) E 200 mmol r borate pH 10.5 V 25 kV Analysis of the monosaccharide units of the polysaccharides from Flos matricariae... 

---