Mass spectrometry imaging applications

In Chapter 4, titled Principles of Mass Spectrometry Imaging Applicable to Thin-Layer Chromatography, the authors first introduce a budding analytical approach known as imaging mass spectrometry (IMS) strategy and then present some successful examples of its practical applications. Then, they introduce in detail three mass spectrometric techniques as those routinely used within the framework of IMS. These are secondary mass spectrometry (SIMS), matrix-assisted laser desorption/ ionization (MALDI-IMS), and desorption electrospray ionization (DESI). Finally, the authors discuss the advances and bottlenecks of these techniques when applied to TLC. [Pg.8]

A Principles of Mass Spectrometry Imaging Applicable to Thin-Layer Chromatography... [Pg.59]

Applications Table 8.58 shows the main fields of application of inorganic mass spectrometry. Mass-spectrometric techniques find wide application in inorganic analysis, and are being used for the determination of elemental concentrations and of isotopic abundances for speciation and surface characterisation for imaging and depth profiling. Solid-state mass spectrometry is usable as a quantitative method only after calibration by standard samples. [Pg.650]

Sugiura Y, Shimma S, Setou M. Two-step matrix application technique to improve ionization efficiency for matrix-assisted laser desorption/ionization in imaging mass spectrometry. Anal. Chem. 2006 78 8227-8235. [Pg.388]

Imaging mass spectrometry by LA-ICP-MS can be employed for studies of homogeneous element distribution in material science (e.g., in semiconductors or ceramics) for future application in the microelectronics industry. [Pg.293]

Biological and medical imaging from single proteins to the whole human brain to provide graphic displays of anatomic detail and physiological function. Several applications in imaging mass spectrometry in human brain research are summarized in Section 9.5.7 ... [Pg.339]