MALDI-ToF imaging mass spectrometry

MALDI-Fourier transform ion cyclotron resonance mass spectrometry MALDI-Q-ion mobility-TOFMS MALDI-Quadrupole-ion-trap-TOF mass spectrometry MALDI-TOF-imaging mass spectrometry MALDI Time-of-flight mass spectrometry Magnetic resonance imaging Matrix solution fixation Moxifloxacin... 

Weidner, S., Knappe, P., and Panne, U. MALDI-TOF imaging mass spectrometry of artifacts in dried droplet polymer samples. Anal. Eioanal. Chem., 401, 127-134. 

E., Urbani, A., Federici, G. (2005) Analytical assessment of MALDI-TOF imaging mass spectrometry on this histological samples. An insight into proteome investigation. Clin Chim Acta, 357, 210-218. 

Hayasaka,T., et al. (2008) Matrix-assisted laser desorption/ ionization quadrupole ion trap time-of-flight (MALDI-QIT-TOF)-based imaging mass spectrometry reveals a layered distribution of phospholipid molecular species in the mouse retina. Rapid Communications in Mass Spectrometry, 22, 3415-3426. 

Key words Imaging mass spectrometry, mass spectrometric imaging, MALDI-TOF/TOF,... 

Weidner SM, Falkenhagen J. LC-MALDI-TOF imaging MS a new approach in combining chromatography and mass spectrometry of copolymers. Anal Chem 2011 83 9153-9158. 

A modified version of 2DE and gel image analysis, with silver staining, autoradiography, and protein identification and measurement of peptide mass, uses matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) as a rapid and sensitive technique for identifying peptides. MALDI-TOF-MS applies well to protein detection in biological fluids.56 A second advantage of this technique is... 

The MALDI-Fourier Transform Ion Cyclotron Resonance Mass Spectrometry (MALDI-FT-ICR-MS) and MALDI-Quadrupole-Ion-trap-TOF Mass Spectrometry (MALDI-QIT-TOF-MS) can be used on IMS. The FT-ICR-MS could provide the high resolution, expansive mass range and high sensitivity imaging MS data and good for determining the elemental composition of small molecules [60],... 

Early attempts to develop patterns of specific compounds and proteins were based on tissue homogenates (Bums, 1982 Jimenez et al., 1997 Mitchell et al., 1997). Tissue profiling, or more accurately called tissue imaging, based on direct mass spectrometry measurements is a much younger area of research which started being developed in late 90s when MALDI-TOF-MS measurements were performed on intact tissue sections (Chaurand et al., 1999). 

Benabdellah, E, Seyer, A., Quinton, L., Touboul, D., Benabdellah, A., Laprevote, O. (2010) Mass spectrometry imaging of rat brain sections nanomolar sensitivity with MALDI versus nanometer resolution by TOF-SIMS. Anal Bioanal Chem., 396,151-162. 

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