Magnetic resonance spectrometry

Pullen, F. S., Swanson, A. G., Newman, M. J. and Richards, D. S., On-line liquid chromatography/nuclear magnetic resonance spectrometry — a powerful spectroscopic tool for the analysis of mixtures of pharmaceutical interest, Rapid Comm. Mass. Spectr., 9, 1003, 1995. 

Fourier Transform Mass Spectrometry Fourier Transform Nuclear Magnetic Resonance Spectrometry... 

Both absorption and emission may be observed in each region of the spectrum, but in practice only absorption spectra are studied extensively. Three techniques are important for analytical purposes visible and ultraviolet spectrometry (electronic), infrared spectrometry (vibrational) and nuclear magnetic resonance spectrometry (nuclear spin). The characteristic spectra associated with each of these techniques differ appreciably in their complexity and intensity. Changes in electronic energy are accompanied by simultaneous transitions between vibrational and rotational levels and result in broadband spectra. Vibrational spectra have somewhat broadened bands because of simultaneous changes in rotational energy, whilst nuclear magnetic resonance spectra are characterized by narrow bands. 

Table 9.1 Components of instruments used for ultraviolet, visible, infrared and magnetic resonance spectrometry. 

Nuclear magnetic resonance spectrometry has been used to quantitate aspirin in a combination product with a coefficient of variation of 1.1.102 For quantitation, the shift at 2.3 ppm representing the ester methyl group was used. 

Using circular dichroism and nuclear magnetic resonance spectrometry, Veatch and coworkers1 established that four conformational species of gramicidin A exist in solution. Two were postulated to be helixes of opposite handedness. 

The second basic approach to characterizing seawater DOM is to concentrate a fraction of the total mixture by chemical or physical means into either dry powder or concentrated solution. The solution can be analyzed using a wide array of methods (e.g., elemental analysis, biomarker analysis, mass, or nuclear magnetic resonance spectrometry) to which these isolates are amenable. 

The isolated 1-indanol was collected and 1 L of the solution was submitted for GC-MS analysis, as described above, and the compound identity was confirmed by nuclear magnetic resonance spectrometry. ... 

Gilpin, R.K. and Gangoda, M.E., Nuclear magnetic resonance spectrometry of alkyl ligands immobilized on reversed phase liquid chromatographic surfaces, Anal. Chem., 56, 1470, 1984. 

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