Macromers poly based

The study of acid-base interaction is an important branch of interfacial science. These interactions are widely exploited in several practical applications such as adhesion and adsorption processes. Most of the current studies in this area are based on calorimetric studies or wetting measurements or peel test measurements. While these studies have been instrumental in the understanding of these interfacial interactions, to a certain extent the interpretation of the results of these studies has been largely empirical. The recent advances in the theory and experiments of contact mechanics could be potentially employed to better understand and measure the molecular level acid-base interactions. One of the following two experimental procedures could be utilized (1) Polymers with different levels of acidic and basic chemical constitution can be coated on to elastomeric caps, as described in Section 4.2.1, and the adhesion between these layers can be measured using the JKR technique and Eqs. 11 or 30 as appropriate. For example, poly(p-amino styrene) and poly(p-hydroxy carbonyl styrene) can be coated on to PDMS-ox, and be used as acidic and basic surfaces, respectively, to study the acid-base interactions. (2) Another approach is to graft acidic or basic macromers onto a weakly crosslinked polyisoprene or polybutadiene elastomeric networks, and use these elastomeric networks in the JKR studies as described in Section 4.2.1. 

Cho, C.S. Han, S.Y. Ha, J.H. Kim, S.H. Lim, D.Y. Clonazepam release from bioerodible hydrogels based on semi-interpenetrating polymer networks composed of poly(epsilon-caprolactone) and poly(ethylene glycol) macromer. Int. J. Pharm. 1999, 181, 235-242. 

Sawhney, A. S., Pathlak, C. P. and Hubbel, J. A., Bioerodible hydrogels based on photo-polymerized PEG-co-poly(x-hydroxy acid) diacrylate macromers. Macromolecules, 26, 581, 1993. 

Donini et al. reported the preparation of poly(methacrylic add-g-polyethylene glycol) nanospheres by solntion or precipitation polymerization. The free radical polymerization of methacryUc acid with PEG macromer was carried out using a photoinitiator in water. Pluronics-based polymers were used to prevent the aggregation of these nanospheres and to render than redispersion ability. 

A.S. Sawhney, C.P. Pathak, J.A. Hubbell, Bioerodible hydrogels based on photopolymerized poly(ethylene glycol)-co-poly(.alpha.-hydroxy acid) diacrylate macromers. Macromolecules 26 (1993) 581-587, doi 10.1021/ma00056a005. 

Sawhney, A.S., Pathak, C.P., and Hubell, J.A., 1993, Bioerodible Hydrogels Based on Photopolymerized Poly(ethylene glycol)-co-poIy(a-hydroxy acid) Diacrylate Macromers. Macromolecules, 26 581... 

Hacker MC, Klouda L, Ma BB, Kretlow JD, Mikos AG. Synthesis and characterization of injectable, thermally and chemically gelable, amphiphihc poly(N-iso-propylacrylamide)-based macromers. Biomacromolecules 2008 9(6) 1558-1570. 

Titmner MD, Shin H, Horch RA, Ambrose CG, Mikos AG. In vitro cytotoxicity of injectable and biodegradable poly(propylene fumaratej-based networks unreacted macromers, cross-linked networks, and degradation products. Biomacromolecules 2003 4(4) 1026-1033. 

Zhao, S., Cao, M., Li, H., Li, L., Xu, W. Synthesis and characterization of thermosensitive semi-ipn hydrogels based on poly(ethylene glycol)-co-poly(epsilon-caprolactone) macromer, n-isopropylacrylamide, and sodium alginate. Carbohydrate Research 345, 425 31 (2010)... 

D Angelo S, Galleti P, Maglio G, Malinconico M, Morelli P, Palumbo R and Vignola M C (2001) Segmented poly (ether-ester-amide)s based on poly (L,lrlactide) macromers. Polymer 42 3383-3392. 

Santerre, J. P., K. Woodhouse, G. Laroche, and R. S. Labow 2005. Understanding the biodegradation of polyurethanes From classical implants to tissue engineering materials. Biomaterials. 26 7457-70. Sawhney, A. S., C. P. Pathak, and J. A. Hubbell 1993. Bioerodible hydrogels based on photopolymerized poly(ethyleneglycol)-co-poly(alpha-hydroxyacid) diacrylate macromers.Macromo/ec /es. 26 581-87. Sciannamea, V., R. Jerome, and C. Detrembleur 2008. In-situ nitroxide-mediated radical polymerization (NMP) processes Their understanding and optimization. Chemical Reviews. 108 1104-26. 

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